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MSK Test 1 > Development of PNS > Flashcards

Development of PNS Flashcards

1
Q

4th somite and above (superiorly)

A

brain

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2
Q

below 4th somite (5th…) (inferiorly)

A

spinal cord

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3
Q

Gray Matter

A

location of the cell bodies of the neurons that make the H shape in the spinal cord; they are not myelinated

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4
Q

Dorsal or posterior horn

A

sensory (afferent neurons)

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5
Q

Lateral horns

A

autonomics; only T1-L2

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6
Q

Anterior or ventral horns

A

motor (efferent nuerons)

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7
Q

White Matter

A

Mainly myelinated axons surrounding the H

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8
Q

Dorsal or posterior funiculus

A

sensory axons

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9
Q

Lateral funiculus

A

sensory and motor axons

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10
Q

Ventral or anterior funiculus

A

primarily motor axons

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11
Q

Alar Plate

A

Sensory neurons that stay completely in CNS

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12
Q

Basal Plate

A

motor neurons in skeletal muscle and pre-synaptic neurons for autonomics

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13
Q

Sulcus limitans

A

separates the Alar and Basal plate

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14
Q

Ventricular zone

A

right next to neural canal; stem cells can give rise to other cells to migrate up to intermediate zoneor stay and give rise to epindymoblast and then ependymal cells which will line ventricles and central canal

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15
Q

choroid plexus cell

A

makes CSF; comes from epindymoblast

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16
Q

Intermediate zone

A

stem cells that migrate in and form neurons, astrocytes (structural), and other cells; gray matter

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17
Q

Marginal zone

A

Axons that are myelinated; oligodendrocytes in CNS and Schwann cells in PNS

18
Q

Arising from neural tube (neuroectoderm)

A

dendrites, astrocytes, oligodendrocyte, and the choroid plexus

19
Q

Microglial cells

A

arise from mesoderm; monocytes of brain and spinal cord (macrophages)

20
Q

Position of spinal cord in newborns

A

L2 or L3; must go lower for puncture

21
Q

position of spinal cord in adults

A

L1 or L2

22
Q

Give rise to spinal ganglion cells and sensory neurons in periphery

A

neural crest cells

23
Q

How to make alar plate

A

high BMP from roof plate and surface ectoderm activate PAX3 and PAX7; DORSAL

24
Q

how to make basal plate

A

High Shh from notochord and floor plate activated NKX2.2k and NKX6.1; VENTRALLY

25
Q

how to make ventral motor neurons

A

slightly less Shh and slightly more BMP activates NKX6.1 and PAX6

26
Q

GSE

A

General somatic efferent; motor neurons for muscle from somites; from NEUROECTODERM

27
Q

GVE

A

General visceral efferent; autonomic motor neurons to smooth and cardiac muscle; from NEUROECTODERM

28
Q

SVE

A

Special (brachial) visceral efferent; motor neurons for muscles derived from pharyngeal arches; from NEUROECTODERM

29
Q

GSA

A

General somatic afferent; sensory neurons in skin, joint capsules, tendons, muscles; from ectoderm or adjacent to ectoderm; NEURAL CREST DERIVED

30
Q

GVA

A

General visceral afferent; sensory neurons from endoderm or mesoderm derived adjacent to endoderm; organs; NEURAL CREST DERIVED

31
Q

SSA

A

Special somatic afferent; hearing, balancing, and sight

32
Q

SVA

A

Special visceral afferent; taste and smell

33
Q

short, myelinated fibers derived from neuroectoderm

A

Pre-ganglionic cells from spinal cord of sympathetic NS

34
Q

longer, not myelinated fibers derived from neural crest

A

post-ganglionic cells from spinal cord of sympathetic NS

35
Q

long myelinated from neuroectoderm

A

pre-ganglionic of parasympathetic

36
Q

short not myelinated from neural crest

A

post-ganglionic of parasympathetic; found in walls of the organ

37
Q

sources of PNS

A

neural crest and ectodermal placodes

38
Q

cranial nerves that parasympathetic travel on

A

3,7,9, and 10

39
Q

sacral nerves for parasympathetic

A

S2, 3, and 4

40
Q

when does the CNS become myelinated

A

6th month through puberty; from neuroectoderm

41
Q

PNS myelination timeline

A

4th month in utero when baby kicks; motor before sensory; SCHWANN cells; from neural crest

MSK Test 1 (11 decks)

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