Development of CNS

Question 1

Nervous system originate from?

Answer 1

Ectoderm

Question 2

Describe early development of CNS

Answer 2

• Nervous system originate from the ectoderm.
  
  • It folds around itself to form a tube
• It has both an anterior-posterior and dorso-ventral axis

Question 3

Progenitors divide?

Answer 3

either symmetrically or asymmetrically at the ventricle

Question 4

The neural network is refined by cell death (apoptosis) and ?

Answer 4

pruning of synapses/neurites

There are more synapses in the body than needed, pruning helps “clear” the pathway

Question 5

Neurotrophic factors

Answer 5

support the survival of connected neurons