Descending Control, M1, Spine Flashcards
Lectures 14/15/16
Area M1
Primary motor cortex
Area S1
Somatosensory cortex
Is M1 rostral/caudal to the premotor cortex?
caudal (posterior)
Betz cells
-large layer 5 neurons that send AP down descending spinal tract
If you were to cut M1 in the frontal plane, describe the areas of processing from medial to lateral…
(Medial) lower extremity, trunk, upper extremity, face (lateral)
Which areas of the body have the most innervations in M1?
Face, hands = fine motor control, dexterity (less force)
A pulse is sent into a monkey for 50ms, then 500ms, what pattern was noticed?
The longer the stimulus, the more complex movements occurred
By viewing EMG readings what did we notice about the order of M1 activation and muscle contraction?
M1 is activated before movement
What happens when we move outside of a neurons optimal movement?
The neuron decreases firing (goes silent)
Explain the concept of optimal movement
Each neuron is tuned to a particular direction of movement
Population vector
average vector from individual M1 neurons
What does the population predict (proceed)?
The observed movement vector (M1 fires first!)
How is the M1 population vector being used in technology?
-spinal cord injury implants
-can respond w/ mechanical exoskeleton/robots
What info is relayed by the ventral posterior medial nucleus (VPM)?
Info about neck/face (think: medial as central as “headquarters)
What info is relayed by the ventral posterior lateral nucleus (VPL)?
Info from below neck, body (think: lateral like peripheral and limbs)
The motor homunculus of the somatosensory cortex (S1) is a…
somatotopic map of the body
What does it mean that S1 is plastic?
Subject to change depending on use (“use it or lose it”)
Do phantom limb sensations originate from M1 or S1
S1
When do patients experience phantom pain?
-when the S1 is in the process of remapping
-includes shrinking sensations
Descending tracts
-send motor commands
-include lateral corticospinal tract (LCT), and ventral corticospinal tract (VCT)