Dermatology and Rheumatology

Question 1

Lofgren’s Syndrome =

Answer 1

= form of acute sarcoid

Question 2

Sedating anti-histamine

Answer 2

Chlorphenamine

Question 3

RF for Pseudogout (4)

Answer 3

Haemochromatosis
Hyperparathyroidism
Acromegaly
Wilson’s Disease

Question 4

Seborrhoeic Dermatitis
- Location
- Associations (2)

Answer 4

Usually in skin folds
Assoc: HIV, Parkinson’s Disease

Question 5

Diffuse Systemic Sclerosis
- Feature
- Antibody

Answer 5

ILD
anti-Scl-70

Question 6

Limited Systemic Sclerosis
- Pattern of scleroderma
- Antibody

Answer 6

Skin below elbow and below the knees: CREST syndrome
anti-centromere

Question 7

Still’s Disease - antibody features

Answer 7

Autoantibody negative

Question 8

Erythema ab igne
- What is it?
- Association

Answer 8

= lace pattern rash associated with extensive heat exposure
e.g. old biddie sitting by the fire
SCC

Question 9

Dermatitis in hands, feet, head and perianal distribution
- Name
- Association

Answer 9

= acrodermatitis
- red crusted lesions, affecting the acral distribution (distal part of limbs, think acral melanoma)
Zinc deficiency

Question 10

Dermatomyositis
- presentation (3)
- association
- antibody

Answer 10

Macular rash on back and extensor aspect of arms
Proximal muscle weakness
Helioptrope rash
Associated with malignancy e.g. lung cancer
anti-Jo1

Question 11

Alternative name for anti-Jo1 antibody

Answer 11

histidine-tRNA ligase antibody

Question 12

Dose of steroid and duration requiring bone protection

Answer 12

7.5mg prednisolone or more daily for 3 months

Question 13

Vilocaceous border

Answer 13

= pyoderma gangrenosum

Question 14

Finding in Paget’s Disease

Answer 14

Increased hydroxyproline
= sign of increased bone turnover, main problem in Paget’s disease

Question 15

Gingival hyperplasia
Two culprit medications

Answer 15

Amlodipine
Phenytoin

Question 16

Management of multi-bacillary leprosy

Answer 16

DRC - endemic in the Congo
Dapsone
Rifampicin
Clofazimine

Question 17

Trichophyton sonsurans =

Answer 17

Tinea capitis

Question 18

Management of pyoderma gangrenosum

Answer 18

Topical steroid

Question 19

HLA association with chronic plaque psoriasis

Answer 19

HLA CW6

Question 20

Behcet’s vasculitis - where can it affect

Answer 20

Can also affect veins

Question 21

Scleroderma renal complication?

Answer 21

Renal crisis
= severe HTN, haemolytic anaemia, other features of sclerodermaB

Question 22

Bone loss in osteoporosis

Answer 22

Mainly trabecular bone loss

Question 23

Cause of livedo reticularis

Answer 23

SLE

Question 24

What is anti-synthetase syndrome?
How does it present?

Answer 24

Similar to dermatomyositis/polymyositis
= acute disease onset, constitutional symptoms, mechanic’s hands, Raynaud’s