Dermatology Flashcards
Which diagnostic preparation can help distinguish eczema from a tinea infection?
KOH prep
What is the risk of using too many steroids on the skin?
Skin atrophy
What type of reaction is atopic dermatitis?
Type IV hypersensitivity
What are common causes of atopic dermatitis?
poison ivy
nickel
topical abx
What type of allergy is latex?
Type I hypersensitivity
What is seborrheic dermatitis?
Chronic inflammatory to Malassezia furfur
What is the treatment of seberrhoic keratosis?
Selenium sulfide or zinc pyrithione shampoos
What is stasis dermatitis?
Lower extremity dermatitis due to venous HTN
What is the treatment of venous stasis?
Leg elevation
Compression stockings
Emollients
Topical steroids
What is the Koebner phenomenon?
Trauma from psoriasis
What is Auspitz sign?
Pinpoint bleeding when a psoriasis scale is scraped
Histogically what is seen in a psoriasis biopsy?
Thick epidermis Elongated rete ridges Absent granular cell layer Preservation of nuclei in the stratum corneum Sterile neutrophilic infiltrate
How do you treat psoriasis -
Mild?
Severe form?
Steroids topical
Methotrexate
anti TNF
UV light therapy if very severe
What causes urticaria?
Histamine and PG from mast cells in a Type I hypersensitivity
What is the treatment of urticaria?
systemic antihistamines
When does a drug eruption happen?
7-14 days after exposure.
If it occurs within 1-2 days of starting a new drug it is likely not the causative agent
What are the characteristic lesions of erythema multiforme?
Targenoid lesions
What is Stevens-Johson Syndrome?
Life threatening exfoliative mucocutaneous disease
What is the difference between SJS and TEN?
Epidermal seperation < 10% SJS BSA
Epidermal seperation > 30% TEN BSA
In which illness is Nikolsky sign positive?
SJS
TEN
What are some causes of SJS?
Penicillin Sulfonamide Seizure medication Allopurinol Cephalosporins Radiotherapy
What is erythema nodosum caused by?
Infection: streptococcus, coccidiodes, yersinia, TB
Drug reaction: OCP, abs, sulfonamide
Which number is oral herpes?
HSV-1
Which number is oral herpes?
HSV-2