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Small animal medicine II > Dermatology > Flashcards

Dermatology Flashcards

1
Q

What is Eosinophilic granuloma complex?

A

A skin condition with a spectrum of patterns on the skin leading to a variety of disease proceses

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2
Q

What are the three presentations of EGC?

A
  1. ) Indolent ulcers
  2. ) Eosinophilic plaques
  3. ) Collagenolytic granuloma
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3
Q

What are some causes of EGC?

A

Allergies - fleas, food
Infectious - parasites, bacteria,
Trauma
Genetics

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4
Q

What do indolent ulcers look like?

A

Well-circumscribed, proliferative inflammatory lesions on the LIP.

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5
Q

T/F: Indolent ulcers are non-painful and non-pruritic.

A

True

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6
Q

What do eosinophilic plaques look like?

A

Well circumscribed, red-yellow, ulcerated edematous on the inguinal area, abdomen, and thighs

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7
Q

T/F: Eosinophilic plaques are non-pruritic.

A

False. Intensely pruritic

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8
Q

What do collagenolytic granulomas look like?

A

Well circumscribed, nodular and firm yellow-pink lesions on the chin or limbs

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9
Q

T/F: Collagenolytic granulomas are non-painful and non-pruritic.

A

True

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10
Q

Where are atypical eosinphilic granulomas usually seen?

A

On the nose or ears.

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11
Q

How do you diagnose EG?

A

Cytology, histo, culture

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12
Q

How do you treat EGC?

A

strict parasitic control, steroids, immunomodulators, potentially surgery

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13
Q

How do you treat feline acne?

A

Treat the secondary infection and give human acne meds - benzoyl peroxide

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14
Q

What are the infectious causes of feline leprosy?

A

Nocardia, actinomyces, mycobacterium, dermatomycoses

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15
Q

What are the CxS of feline leprosy?

A

Nodules that burst and drain

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16
Q

How do you diagnose feline leprosy?

A

full skin exam, biopsy

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17
Q

T/F: Immune-mediated skin disorders are rare skin conditions

A

True. 1.4% of skin disorders

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18
Q

How do you diagnose immune-mediated skin disorders?

A

Histopathology with multiple biopsies

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19
Q

How do you treat immune-mediated skin disorders

A

Immunosuppressive drugs like steroids and cyclosporine

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20
Q

What is acantholysis?

A

The loss of intracellular connections between keratinocytes

21
Q

T/F: Pemphigus erythematosus is benign

A

True

22
Q

What is a potential aggravator of pemphigus erythematosus?

A

UV light

23
Q

What might you see with a dog with pemphigus erythematosus?

A

Erythema, dermatitis on face and ears

Oozing crusts, scales, alopecia, erosion, epidermal collarette

Depigmentation on NOSE

24
Q

How can you treat pemphigus erythematosus?

A

Avoid the sun, topical steroids/immunosuppressants

25
Q

What is the most common immune-mediated skin condition?

A

Pemphigus foliaceus

26
Q

What antigen is affected with pemphigus foliaceus?

A

desmoglein 1

27
Q

What are the CxS of pemphigus foliaceus?

A

Pustular dermatitis, crusting on feet, face and ears

Nasal depigmentation

28
Q

What antigen is affected with pemphigus vulgaris?

A

Desmoglein 3

29
Q

What CxS will be seen with pemphigus vulgaris?

A

Erosions and ulcers on the oral cavity, mucocutaneous junctions, and skin (groin)

30
Q

T/F: Prognosis for pemphigus vulgaris is typically poor

A

True

31
Q

How could you treat pemphigus vulgaris?

A

High dose of prednisone and azathioprine

Chlorambucil for cats

32
Q

What very rare condition forms autiantibodies against antigens of the basal cell hemidesmosomes of the skin and mucosa?

A

Bullous pemphigoid

33
Q

What CxS will you see with bullous pemphigoid?

A

subepidermal vesicles and cutaneous lesions on the groin and in the mouth

34
Q

Exposure to what aggravates discoid lupus erythematosus?

A

UV light exposure

35
Q

What types of immune cells predominate with DLE?

A

T-helper cells activated from damage to keratinocytes

36
Q

What are the CxS wth DLE?

A

depigmentation, erythema, scaling of nose leading to erosions, ulcers, and crusts

37
Q

How can you diagnose DLE?

A

histopathology

38
Q

How do you treat DLE?

A

avoid sun, vitamin E, corticosteroids

39
Q

T/F: Etiology of systemic lupus erythematosus is from viruses

A

True, but is multifactorial and also comes from genetics, immune disorders, UV light

40
Q

what CxS will you see on dogs with SLE?

A

Fever, polyarthritis, proteinuria

skin conditions - alopecia, erythema

41
Q

What effects can cutaneous adverse drugs reactions cause?

A

Alopecia, purpura, poor wound healing, hyperpigmentation, pruritis

42
Q

What CxS do you see with erythema multiforme?

A

Acute onset of macules and elevated papules, urticarial plaques

43
Q

Where do you normally see the lesions of erythema multiforme?

A

Ventrum and groin

44
Q

What are the causes of toxic epidermal necrolysis?

A

Drugs, flea dips

45
Q

What CxS are there with toxic epidermal necrolysis?

A

Multifocal or generalized vesiculobullous disease

46
Q

How do you diagnose TEN?

A

full thickness biopsy of affected skin

47
Q

What parts of the body does vasculitis usually affect?

A

Extremities

48
Q

How can you treat vasculitis?

A

Treat underlying disease, pentoxifylline, immunosuppressive/modulary drugs

Small animal medicine II (8 decks)

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