Dermatology

Question 1

What is Eosinophilic granuloma complex?

Answer 1

A skin condition with a spectrum of patterns on the skin leading to a variety of disease proceses

Question 2

What are the three presentations of EGC?

Answer 2

1. ) Indolent ulcers
2. ) Eosinophilic plaques
3. ) Collagenolytic granuloma

Question 3

What are some causes of EGC?

Answer 3

Allergies - fleas, food
Infectious - parasites, bacteria,
Trauma
Genetics

Question 4

What do indolent ulcers look like?

Answer 4

Well-circumscribed, proliferative inflammatory lesions on the LIP.

Question 5

T/F: Indolent ulcers are non-painful and non-pruritic.

Answer 5

True

Question 6

What do eosinophilic plaques look like?

Answer 6

Well circumscribed, red-yellow, ulcerated edematous on the inguinal area, abdomen, and thighs

Question 7

T/F: Eosinophilic plaques are non-pruritic.

Answer 7

False. Intensely pruritic

Question 8

What do collagenolytic granulomas look like?

Answer 8

Well circumscribed, nodular and firm yellow-pink lesions on the chin or limbs

Question 9

T/F: Collagenolytic granulomas are non-painful and non-pruritic.

Answer 9

True

Question 10

Where are atypical eosinphilic granulomas usually seen?

Answer 10

On the nose or ears.

Question 11

How do you diagnose EG?

Answer 11

Cytology, histo, culture

Question 12

How do you treat EGC?

Answer 12

strict parasitic control, steroids, immunomodulators, potentially surgery

Question 13

How do you treat feline acne?

Answer 13

Treat the secondary infection and give human acne meds - benzoyl peroxide

Question 14

What are the infectious causes of feline leprosy?

Answer 14

Nocardia, actinomyces, mycobacterium, dermatomycoses

Question 15

What are the CxS of feline leprosy?

Answer 15

Nodules that burst and drain

Question 16

How do you diagnose feline leprosy?

Answer 16

full skin exam, biopsy

Question 17

T/F: Immune-mediated skin disorders are rare skin conditions

Answer 17

True. 1.4% of skin disorders

Question 18

How do you diagnose immune-mediated skin disorders?

Answer 18

Histopathology with multiple biopsies

Question 19

How do you treat immune-mediated skin disorders

Answer 19

Immunosuppressive drugs like steroids and cyclosporine

Question 20

What is acantholysis?

Answer 20

The loss of intracellular connections between keratinocytes

Question 21

T/F: Pemphigus erythematosus is benign

Answer 21

True

Question 22

What is a potential aggravator of pemphigus erythematosus?

Answer 22

UV light

Question 23

What might you see with a dog with pemphigus erythematosus?

Answer 23

Erythema, dermatitis on face and ears

Oozing crusts, scales, alopecia, erosion, epidermal collarette

Depigmentation on NOSE

Question 24

How can you treat pemphigus erythematosus?

Answer 24

Avoid the sun, topical steroids/immunosuppressants

Question 25

What is the most common immune-mediated skin condition?

Answer 25

Pemphigus foliaceus

Question 26

What antigen is affected with pemphigus foliaceus?

Answer 26

desmoglein 1

Question 27

What are the CxS of pemphigus foliaceus?

Answer 27

Pustular dermatitis, crusting on feet, face and ears Nasal depigmentation

Question 28

What antigen is affected with pemphigus vulgaris?

Answer 28

Desmoglein 3

Question 29

What CxS will be seen with pemphigus vulgaris?

Answer 29

Erosions and ulcers on the oral cavity, mucocutaneous junctions, and skin (groin)

Question 30

T/F: Prognosis for pemphigus vulgaris is typically poor

Answer 30

True

Question 31

How could you treat pemphigus vulgaris?

Answer 31

High dose of prednisone and azathioprine Chlorambucil for cats

Question 32

What very rare condition forms autiantibodies against antigens of the basal cell hemidesmosomes of the skin and mucosa?

Answer 32

Bullous pemphigoid

Question 33

What CxS will you see with bullous pemphigoid?

Answer 33

subepidermal vesicles and cutaneous lesions on the groin and in the mouth

Question 34

Exposure to what aggravates discoid lupus erythematosus?

Answer 34

UV light exposure

Question 35

What types of immune cells predominate with DLE?

Answer 35

T-helper cells activated from damage to keratinocytes

Question 36

What are the CxS wth DLE?

Answer 36

depigmentation, erythema, scaling of nose leading to erosions, ulcers, and crusts

Question 37

How can you diagnose DLE?

Answer 37

histopathology

Question 38

How do you treat DLE?

Answer 38

avoid sun, vitamin E, corticosteroids

Question 39

T/F: Etiology of systemic lupus erythematosus is from viruses

Answer 39

True, but is multifactorial and also comes from genetics, immune disorders, UV light

Question 40

what CxS will you see on dogs with SLE?

Answer 40

Fever, polyarthritis, proteinuria skin conditions - alopecia, erythema

Question 41

What effects can cutaneous adverse drugs reactions cause?

Answer 41

Alopecia, purpura, poor wound healing, hyperpigmentation, pruritis

Question 42

What CxS do you see with erythema multiforme?

Answer 42

Acute onset of macules and elevated papules, urticarial plaques

Question 43

Where do you normally see the lesions of erythema multiforme?

Answer 43

Ventrum and groin

Question 44

What are the causes of toxic epidermal necrolysis?

Answer 44

Drugs, flea dips

Question 45

What CxS are there with toxic epidermal necrolysis?

Answer 45

Multifocal or generalized vesiculobullous disease

Question 46

How do you diagnose TEN?

Answer 46

full thickness biopsy of affected skin

Question 47

What parts of the body does vasculitis usually affect?

Answer 47

Extremities

Question 48

How can you treat vasculitis?

Answer 48

Treat underlying disease, pentoxifylline, immunosuppressive/modulary drugs