Dermatology Flashcards
What are the 4 types of Diaper Dermatitis
Irritant: Caused by urine or feces
Candidiasis: Yeast with pustules
Allergic
Streptococcal: Bright red perianal patches with satellite lesions
Tx for Diaper Dermatitis
Air/Barriers (paste/ointment), Clean, Dispose of diapers, Educate Steroid Ointment 1% Hydrocortisone Abx: Cephalexin Mupirocin Topical Antifungal: Miconazole for yeast
What is Perioral Dermatitis
Inflammatory papules around mouth, nose, or eyes
Tx for Perioral Dermatitis
Topical: Metronidazole or Erythromycin
Oral: Tetracycline, Minocycline, Doxycycline
What is the most common drug that causes drug eruptions
Penicillin
What is DRESS Syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms
Associated with Drug Eruptions
Rash, Fever, Lymphadenopathy, Hematologic Abnormalities, Hepatitis, Involvement of lungs, kidney, heart, or pancreas
Tx for drug eruptions
Discontinue drug
If IgE mediated use Epinephrine, H1 and H2 blockers, systemic corticosteroids
What do you see with Erythema Multiforme
Target Lesion
Dusty-violet red, purpuric macule/vesicle in center surrounded by pale edematous rim and peripheral red halo
What is Erythema Multiforme
Acute self-limiting IV rxn
Associated with Herpes
Tx for Erythema Multiforme
Avoid prescipitating cause
Control HSV: Acyclovir
What is Stevens Johnson Syndrome
Drug eruption due to Sulfa drug or Anticonvulsants
What lesions are seen with SJS
Mucocutaneous blistering with skin detachment, usually >10%
What sign is seen with SJS
Positive Nikolsky’s Sign (blisters pop when you touch them)
Tx for SJS
Remove agent
Burn unit for skin tx
What is Toxic Epidermal Necrolyisis (TEN)
Drug eruption, more severe than SJS
What lesions are seen with Toxic Epidermal Necrolysis
Same as SJS but with skin detachment >30% of body
What is Lichen Planus
An autoimmune destruction of epidermal cells
What lesions are seen with Lichen Planus
6 P’s: Planar, Purple, Polygonal, Pruritic, Papules, Plaques
Wickham Striae - Lacy reticular white lines covering lesions
Dx for Lichen Planus
Biopsy and Immunofluorescence
Tx for Lichen Planus
Topical Hydrocortisone and/or oral prednisone
What is Pityriasis Rosea
Herald Patch with Christmas Tree pattern
Have mild URI sx, scaly lesions
Tx for Pityriasis Rosea
Lotions/Emollients
Antihistamines/Antipruritics
What is the process of Acne Vulgaris
Plugged follicles leads to retained sebum, which leads to bacterial overgrowth, follicle releases which leads to increased sebum
What hormones play a major role in Acne Vulgaris
Androgens
What is a blackhead
Open Comedone: Flat slightly elevated papules, central opening with blackened keratin
What is a whitehead
Closed Comedone: Yellowish papules
Tx for all stages of Acne Vulgaris
Mild Comedonal: Topical Retinoid (Tretinoin Cream)
Mild Pustular: Tretinoin + Benzoyl Peroxide +/- Abx
Moderate Pustular: Tretrinoin + Benzoyl Peroxide + Oral Abx (Tetracycline, Doxycycline, or Minocycline)
Severe Acne: Isotretinoin (Accutane)
What causes Lice (Pediculosis)
Pediculus Hummanus
Dx for Lice
See nits on hair shaft
Tx for Lice
Permethrin, Malathion
What causes Scabies
Sarcoptes Scabiei
Sx for Scabies
Severe itching, pruritic burrows, red papules/nodules on scrotum, shaft, and glans penis
Dx for Scabies
Mites, eggs or feces on microscopic slide
Tx for Scabies
Treat entire family with 4% Permetrhin cream once for 8-12 hours
Wash all clothes in hot water and dry in hot dryer
What is Androgenic Alopecia
Non-Scarring hair loss due to androgenic overactivity
Tx for Androgenic Alopecia
Minoxidil
What are the 5 childhood exanthems
Rubeola (Measles) Rubella (German Measles) Varicella (Chicken Pox) Erythema Multiform (Fifths Disease) Roseola (Sixths Disease)
What causes Rubeola (Measles)
Paramyxovirus
Sx of Rubeola (Measles)
Cough, Coryza, Conjunctivitis
Koplik Spots
Starts at hairline, moves to extremities then palms/soles
Most common complication for Rubeola (Measles)
Otitis Media