Dermatology 2 inc Ear Surgery Flashcards
When are anti-histamines used in pruitic skin disease?
Before mast cell degranulation. i.e. good for seasonal allergies. None licence.
Time of onset for a) prednisalone b) ciclosporin c) Essential fatty acids
a) pred good for short time control (day)
b) Ciclosporin = Cacineurin inhibitor = TAKES 4 WEEKS
c) Essential fatty acids = TAKES WEEKS
Ciclosporin
Cacineurin-inhibitor.
More targetted T cell suppression than glucocorticoids
4 weeks to work..
Transient voming and diarhooea, hirsuitism, gingival hyperplasia
ASIT how does it work. How long does it take?
Immunodoulation. Allergen-specific immunotherapy. Injections of allergen extract subcut at increases quantities to patients with atopic dermatitis. Decrease inflamm cells.
Full effect may take 9 months
Problem associated with intradermal test
Need to be off steroids for good test results. Can be difficult if severely pruitic.
Serology less affected.
Cons of ASIT
Antigen specific immunodulation therapy.
Anaphylaxis therefore first few injections keep in practice.
Depigmentation of nasal planum and exfolaitive erythroderma on dogs nose could be….
Epitheloptrophic lymphoma. REMEMBER MORE SERIOUS Ddx when treating skin disease
in dogs 90% of superficial pyoderma is caused by
Staphlococcus pseudointermedius.
Antirobe is…
It is not recommended
Clindamycin. Narrow spec.
NOT RECOMMENDED FOR RECURRENT CASES.
Treatment for Superficial pyoderma
Use of topical antibacterial shampoos e.g.. Clorhexidine ALONE Or Clindamycin (Antirobe), Cefalexin, Co-Amoxiclav (Synulox)
Treatment PLAN for deep pyoderma
Only 60-90% S.pseudointermedius. Based on culture and antimicrobial sensitivity testing. While waiting for lab results cytology If rods = Flouroquinolone Cocci= Cefalexin 2 weeks beyond clinical cure
What dermatological changes would you expect to see in a cow that has ingested St John’s Wart?
PRIMARY PHOTOSENSITISATION
Can be secondary photosensitisation due to liver disease
Most common cattle louse?
Linognathus vituli.
Bovicola bovis
Clinical signs of louse infection in cows
Pruitis, particularly B bovis.
Hair loss due to rubbing.
Neck back shoulders, flank tail base.
What time of year are lice a problem in cattle
Cool months, peak in early spring (more common in housed cattle)
Decline with coat shedding/ solar radiation and higher temperature.
When is the best time to treat louse infection of cows?
Autumn (no lice visible because numbers are so low).
treatment not always justified.
Treatment of Lice in cattle
Autumn. ML’s are very effective (kill all suckling lice and reduce B bovis numbers – pour on)
Cattle Sarcoptic mange- where?
Causes head and tail mange. Mostly in housed cattle. Any age. Transmission by direct contact. Mites survive a few days on fomites.
Treatment of Sarcoptic mange in cattle
Macrocytic Lactones.
Psorptic mange in cattle treatment
Permethrin pour on or Macrocytic Lactones.
Pathogenesis of Psorptic mange in cattle
Starts on shoulders and rump. Papules/Crusting. Quickly affects whole body. Secondary bacterial infections likely.
Difference in area affected between Psorptic mange and Sarcoptic mange and Chorioptic mange.
Sarcoptic: Head/ Tail
Psorptic: Shoulder/Rump
Choroptic=leg mange: Tail mange/ hind limbs
Which type of mange causes ‘leg mange’ and udder, perineum and tail?
Chorioptic mange
Sheep lice
Bovicola ovis. Biting louse
Linognathus ovillus - sucking louse
Sheep body louse=
Biting louse. Bovicola ovis. Rubbing/ biting wool. More important in Merino/Merino type wool. Increased incidence since dipping stoped.
Sheep scab =
Psorptic mange.
Sheep scab clinical signs when is common time?
Pustules, then spreading moist lesions. Extreme pruitis. Fleece becomes matted.
Winter is more favourable to mites than summer. Infections can be latent over winter.