Derm Terms Flashcards
What are some properties of the skin?
protective properties
slightly acid–>antibacterial
synthesizes vitamin D (UVB hitting skin)
photo reactions to drug therapy (via UVA)
What does a phototoxic reaction look like on the skin?
exaggerated sunburns
Describe the anatomy of the skin.
very thin
as cells move up they die
lipids present on outer layer
What determines pliability of the skin?
moisture
dry skin: starts to crack
moisturized: pliable
What are each of the following important for: epidermis, sebaceous gland, sweat gland, and melanocytes
epidermis: dry skin, aging, being a barrier
sebaceous gland: acne, seborrhea
sweat gland: heat-related illness
melanocytes: melanoma, vitiligo, suntan
Which structures are found in the dermis and hypodermis?
dermis: hair follicles, sebaceous and sweat glands
hypodermis: subcutaneous tissue, connective and adipose tissue
Which component of the skin is responsible for sensations of itch, stinging, and pain?
dermis
What are the two types of sweat glands? Where do you find these sweat glands?
eccrine (all over the body) and apocrine (under arms and anogenital area)
What could be a symptom of psoriasis on the toenails?
tiny little pits on the toenail
What is considered to be the biggest barrier to overcome for drug delivery on the skin? What happens if this barrier is compromised?
stratum corneum
if it is compromised then absorption increases
What are the factors affecting drug absorption on the skin?
skin hydration (moist is better)
pH of drug and vehicle
thickness of application (depends on use)
temp of skin (heated skin increases absorption)
damaged skin
If an area is scaly and appears chronic, what is your recommendation?
ointment
How do you measure a fingertip unit?
from the end of the finger to the first crease in the finger
How much area of skin does one FTU cover?
twice the size of a flat adult hand
Which lesions go together in the same groups?
vesicles, blistering, bullae
erythema, wheal, papule, pustule, abscess
crusting, scales, plaque, patch
excoriation