Derm Flashcards
1
Q
What are keratohyalin granules?
A
found in epidermis contain filaggrin, involucrin, and loricirin
2
Q
What is a lamellar granule?
A
aka odland body contain ceramides cholesterol fatty acids hydrolytic enzymes
3
Q
What are the layers of the epidermis in order from out to in?
A
stratum corneum cornified layer stratum granulosum/granular layer stratum spinosum/spinous layer stratum basale/ basal layer
4
Q
Which is the most abundant type of collagen?
A
collagen I present in both the skin and bones
80-90% of collagen
5
Q
What is the second most abundant collagen?
A
type III; increased levels in embryogenesis, infancy and wound healing
6
Q
What collagens are found in basement membrane?
A
IV, VII, and XVII
7
Q
What is morphea?
A
an autoimmune disease that causes sclerosis (thickening of collagen)
joint and neurologic complications
8
Q
What is systemic scleroiss?
A
autoimmmune common in middle aged women; widespread scleroiss Sxs: sclerosis of skin raynauds Telangiectasia Arthritis Internal organ involvment
9
Q
What is erythema nodosum?
A
reactive panniculitis -strep pharyngitis -oral contraceptives -inflammatory bowel disease found in young women tender red nodules on the shiins
