Depression: Meds

Question 0

Advantages of SSRI

Answer 0

few adverse effects; low lethality

Question 1

First line Tx for Depression

Answer 1

SSRIs

Question 2

Toxic effects: SSRI

Answer 2

Serotonin Syndrome (risk increased with MAOI): abd pain, diarrhea, sweating, fever, tachycardia, increased BP, delirium, myoclonus, increased motor activity, irritability, hostility, mood change; severe sx - hyperpyrexia, cardiovascular shock, death

Question 3

Citalopram (Celexa)

Answer 3

SSRI

Question 4

Escitalopram (Lexapro)

Answer 4

SSRI

Question 5

Fluoxetine (Prozac)

Answer 5

SSRI

Question 6

Fluvoxamine (Luvox)

Answer 6

SSRI

Question 7

Paroxetine (Paxil)

Answer 7

SSRI

Question 8

Sertraline (Zoloft)

Answer 8

SSRI

Question 9

Venlafaxine (Effexor)

Answer 9

SNRI

Question 10

Duloxetine (Cymbalta)

Answer 10

SNRI

Question 11

Reboxetine (Vestra)

Answer 11

NRI

Question 12

Bupropion (Wellbutrin)

Answer 12

NDRI

Question 13

Mertazapine (Remeron)

Answer 13

SNDI (Serotonin Norepinephrine Disinhibitor)

Question 14

Amitriptyline (Elavil)

Answer 14

TCA

Question 15

Clomipramine (Anafranil)

Answer 15

TCA

Question 16

Desipramine (Norpramine)

Answer 16

TCA

Question 17

Doxepin (Adapin, Sinequan)

Answer 17

TCA

Question 18

Imipramine (Tofranil)

Answer 18

TCA

Question 19

Nortriptyline (Aventyl, Pamelor)

Answer 19

TCA

Question 20

Protriptyline (Vivactil)

Answer 20

TCA

Question 21

Phenelzine (Nardil)

Answer 21

MAOI

Question 22

Selegiline Transdermal (EMSAM)

Answer 22

MAOI

Question 23

Tranylcypromine (Parnate)

Answer 23

MAOI

Question 24

Toxic effects: TCA

Answer 24

Cardiovascular (i.e. dysrhythmias, tachycardia, MI, heart block)

Question 25

MAOIs

Answer 25

No tyramine

Question 26

Foods containing Tyramine

Answer 26

Avocados, beans, aged meats/fish, most cheeses, beer/wine, foods that contain yeast

Question 27

Toxic effects: MAOI

Answer 27

Hypertensive crisis: severe headache, tachycardia, palpitations, htn, nausea, vomiting