Dementia

Question 1

Cholinesterase Inhibitor

Answer 1

Increase AcH in brain to enhance memory and learning capacity

For dementia

Adverse effects- bradycardia, hypotension

Drug- donepezil

Question 2

NMDA receptor antagonists

Answer 2

Blocks the stimulation of NMDA receptors

Help reduce symptoms of cognitive degeneration

Adverse Effects- hypotension, headache, GI upset , musculoskeletal pain

Drug- memantine