DEEP VEIN THROMBOSIS (DVT) Flashcards
❖ It refers to thrombus formation in the deep veins.
DEEP VEIN THROMBOSIS (DVT)
____ carries more blood compared to ___
VEIN - ARTERY
These veins have valves because the blood should only flow in ___ direction and to prevent ___ of blood.
With the help of muscular contraction, the muscles push the _______.
one - backflow
blood towards the heart
DVT usually occurs in the ____
lower leg
EXPLAIN
Women are 3x more likely than men to have venous ulcer
▪ The estrogen weakens the veins and is a food for cancer cells (99%).
▪ Estrogen increases the HDL production and help s the kidneys in removing uric acid.
▪ After menopause estrogen decreases.
RISK FACTORS – collectively known as
Virchow’s Triad
RISK FACTOR
→ Vascular Wall Injury Examples
▪ Surgery
▪ Trauma (burns)
▪ Indwelling Catheters
▪ Infection
▪ Drug Abuse
▪ Injection of irritating substances such as
antibiotics, steroids, and NSAIDs.
RISK FACTOR
→ Venous Stasis
▪ Immobilization for more than 3 days.
▪ Obstruction or compression of the iliac or femoral vends from:
➢ Abdominal or Pelvic Tumors
➢ Obesity
➢ Pregnancy
▪ Lengthy surgery (more than 30mins)
RISK FACTOR
→ Venous Stasis
▪ Congestive Heart Failure
Right-sided heart failure prevents deoxygenated blood from the vena cava from entering the right atrium. Consequently, it flows downward, leading to an enlargement of the liver (hepatomegaly), and it can result in the accumulation of fluid in the peritoneal cavity (ascites). It can also cause swelling in the legs (dependent edema).
RISK FACTOR
→ Venous Stasis
▪ Shock
Sepsis shock is a condition where an infection triggers the release of chemical mediators. One of the effects is increased capillary permeability, causing plasma to shift into the interstitial space, leaving blood cells within the vessels. This can lead to increased blood viscosity and the potential for clot formation.
➢ Blood consists of plasma and blood cells.
RISK FACTOR
→ Venous Stasis
▪ Varicose Veins
Valves in the veins are not closing completely causing backflow of blood in the lower extremities making the blood stagnant.
❖ COMPLICATIONS OF DVT
→ Pulmonary Embolism
▪ Trouble catching breath
▪ Chest pain
▪ Coughing up blood
▪ Tachycardia
▪ Dizziness or fainting
++ thrombus dislodge from vein and goes with blood going to the lungs
++ lessen oxygenation of the blood
→ CVA or Stroke
❖ MEDICAL MANAGEMENT FOR DVT
Anticoagulants
▪ It inhibits blood coagulation and serve to weaken already formed clots, preventing formation of new clotted blood.
▪ Heparin is given parenterally (IV or SUB-Q)
➢ has short life span and is given frequently
▪ Low-Molecular-Weight Heparin is the drug of choice for patients with DVT.
▪ Enoxaparin (Clexane S.C.) has less bleeding, and the duration of action is longer; given via sub-q.
▪ Oral Warfarin (Coumadin) – 3 to 6 months
➢ AquaMEPHYTON (Vitamin K) is the antidote for Warfarin Toxicity.
➢ Therapeutic Range for the INR is 2-3.
➢ With an INR of 5.9, this client is at great risk for hemorrhage and should be given the vitamin K.
❖ MEDICAL MANAGEMENT FOR DVT
Thrombolytics
▪ It dissolves new clotted blood (within 3 hours).
▪ Thrombolytics are typically administered for a limited duration, typically up to 24 hours, due to the risk of bleeding. After this initial treatment, thrombolytics are discontinued, and heparin is often prescribed as the ongoing anticoagulant therapy.
▪ It is for patients with hemodynamically unstable PE or massive iliofemoral thrombosis.
▪ Tissue Plasminogen Activator (TPA)
➢ common drug used
▪ Assess for internal bleeding: check the IV site for signs of blood, look for bruises, examine for hematuria (blood in the urine), and check for the presence of blood in the stool (black/dark brown).
❖ MEDICAL MANAGEMENT FOR DVT
Antiplatelet
▪ It decreases activation of platelets and prevent new clots from being formed.
▪ Assess a patient who’s receiving anticoagulant therapy for signs and symptoms of bleeding, such as:
➢ bleeding gums
➢ nose bleeds
➢ unusual bruising
➢ bloody urine
➢ black, tarry stools
▪ Advise the patient not to take any medication containing Aspirin of NSAIDs.