Deck 5 Flashcards

1
Q

Haemolytic crisis in sheep

A

copper poisoning

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2
Q

Poisoning with urea - amount in milk

A

> 12 mmol/L

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3
Q

Mechanism of action by heavy metals

A

Combining one or more reactive groups of enzymes that are essential for normal physiological functions - SH groups, which are essential for certain enzymes activity

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4
Q

What are desiccants?

A

herbicides that dry green parts of plant before harvest

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5
Q

Mycotoxin with estrogen-like action

A

Zearalenone

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6
Q

Nicotine belongs to the group of

A

Natural insecticides

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7
Q

What is antagonism?

A

An attenuation or complete elimination of the effect of one poison by another poison

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8
Q

Treatment of urea poisoning

A

acetic acid or hydrochloric acid

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9
Q

Fluoracetates are converted to

A

fluorocitrate, which blocks the tricarboxylic acid cycle (by inhibition of enzyme aconitase)

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10
Q

Ethiology of poisoning in domestic and wildlife animals

A

Pesticides
Fertilizers
Food additives
Industrial emissions
Waste water
Mycotoxins
Alkaloids and glycosides
Poisons of animal origin
Radiotoxins

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11
Q

The most important types of toxic substances

A

Drugs
Additives
Pesticides
Industrial chemicals
Environmental pollutants
Natural toxins and household toxins

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12
Q

Synergism is

A

an amplification of the joint action of two or more toxins having the same biological effect

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13
Q

What is toxicokinetics

A

the study of changes in a poison or its metabolites in the body from the time it enters until it is fully eliminated

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14
Q

The disposition of a toxic compound in a biological system may be divided into

A

Absorption
Distribution
Metabolism
Excretion

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15
Q

Some chemicals are metabolized into more toxic compounds, this is called

A

biotoxification

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16
Q

Pathological derivatives of hemoglobin are

A

Methemoglobin
Carboxyhemoglobin
Cyanhemoglobin
Methemoglobin cyanide
Sulphemoglobin

17
Q

Carbon monoxide affinity to Hb

A

300 times more than oxygen

18
Q

Utilization and fate of ammonia in animal organism

A

Urea is degraded in rumen –> urease and ammonia rise.
Urea –> CO2 + 2NH3 (urease + H2O)
Ammonia is used as source of nitrogen –> AAs, protein.
Ammonia –> liver –> non-essential AAs, urea and glutamine.

19
Q

Which is more toxic - As3+ or As5+?

A

As3+

20
Q

Selenium poisoning can be divided into 3 groups:

A
  1. Acute
  2. Subacute
  3. Chronic
21
Q

Mechanism of antimony

A

Similar to arsenic.
Antiparasitic effect: inhibition of phosphofructokinase –> slows glycolysis –> disturbe energy metabolism of the parasites.

22
Q

What are phenols used for in agriculture?

A

fungicides

23
Q

What does lead inhibit?

A

Protoporfirins synthesis

24
Q

How is poison in the organism converted?

A

Biochemically active substances.
They interact with chemicals and enzymes present in the body to become more complex, simply or moderately altered.

25
Q

What animal is sensitive to molybdenum?

A

Cattle

26
Q

Packaging CHTA

A
  1. Consider every chemical as infectious
  2. Preserve by cooling (not chemicals)
  3. Avoid contamination
  4. Divide samples into equal portions
  5. Pack each sample separately into plastic bags
  6. Label samples in several places
  7. Put into mobile refrigerator/wooden box with lid
27
Q

What are the derivatives of aldehyde?

A

Acetylaldehyde
Metaldehyde
Formaldehyde

28
Q

How do we determine NO3, NO2 and NaCl?

A

water extract

29
Q

How long does carbomate serin persist:

A

1 year

30
Q

Antidote for selenium

A

small amounts of arsenic compounds in water