Deck 4 Flashcards
Dinitrophenols act by
Blocking oxidative phosphorylation
Methemoglobinemia agents
Directly-acting agents
Indirectly-acting agents
Nitrites
Chlorates
Carbamates
Oxides of nitrogen
Aromatic nitro and amino compounds
Herbicide sodium chlorate causes
production of methemoglobin
Amygdalin is
poisonous cyanogenic glycoside - found in many plants (apricot, peach and plum seeds)
ANTU acts
Increase permeability of lung capillaries –> pulmonary edema and accumulation of serous transduate in the lung alveoli
Normal concentration of methemoglobin is
3 +/- 2%
Mycotoxins can be divided into 4 groups according to their effect on organism
- Hepatotoxic effect
- Provoking haemorrhagic syndrome
- Provoking photodynamic effect
- Other effects
DDT, chlordane, dieldrin, aldrin, heptachlor and lindane belong to
Chlorinated hydrocarbon insecticides
Can samples for CHTA be preserved with chemicals?
NO!
Pb is qualitatively determined with
H2SO4 (sulfuric acid)
Brucine is used as a detection solution for qualitative determination of
NO3 (nitrate)
OCB is determined by
gas chromatography
NaCl is determined
by water extract
How is toxic substances determined after adjustment
Water extract
Extraction with organic solvent
Steam distillation
Mineralisation
Zn3P2 is determined
without adjustment
Reinisch test is used for determining
mercury
What system detoxicate MtHb to Hb in organism?
MtHb reduction system by MtHb reductase
Therapy of methemoglobinemia poisoning
Methylene blue
Use of metaldehyde
Muloscide
Poisoning of selenium leads to
loss of hair, hobbling
What does CS2 (carbon disulfide) affect?
Nervous system, cause vomitus, spasms and exitus
Mode of action of alkaloids
Sedative and irritant
Characterize chronic copper intoxication
Haemolytic crisis:
paleness and jaundice, urine is dark brown
What are clover pyretrines made from?
Chrysantheum cineraria folium
Metoxicity and chlorine are
Non-accumulating
What materials contain Cl-?
Thanit letham
What is the end result of acid carbon?
Increased weight with lipid
Persistence of some substances simazin
3 years
What does H2S (hydrogen sulfide) rise in?
Putrification of protein
How is triazin accumulating?
highly accumulating