Deck 3 Flashcards

1
Q

Anticoagulant rodenticides inhibit

A

production of prothrombin

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2
Q

Specific antidote in warfarin poisoning is

A

Vitamin K or K1

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3
Q

Normal percentage of methemoglobin is

A

2-5%

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4
Q

Mycotoxins are

A

toxin forming due to growth of mold

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5
Q

During urea intoxication the pH of rumen

A

increases

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6
Q

MCPA is used as

A

herbicide and algicide

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7
Q

DDT, chlordane, aldrin and heptachlor belong to

A

chlorated hydrocarbon insecticides

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8
Q

Diquat and paraquat are

A

herbicides

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9
Q

Define poisons (Swaga)

A

Poison is every chemical substance qualitatively or quantitatively different from the organism and it is harmful from chemical or physical aspect

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10
Q

Define ethiology of poisoning

A

disease of the organism with certain clinical symptoms caused by abrosbable poison after its income:
per os with food or water
per inhalation
per cutis

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11
Q

What does CHTA consist of?

A

Extraction
Purification
Detection

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12
Q

Prosedure in sampling fish

A

Send the whole fish
Send water from intoxicated area
Map of intoxicated area
Samples from above the possible place of intoxication

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13
Q

Methods for detection of toxic substances

A

Spectrophotometry (UV, IR, visible light)
Physical method
Polarography
Chromatographic methods -TLC, GC, HPLC

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14
Q

Diagnosis of intoxication consists of

A

Anamnesis - gathering all available information
Clinical symptoms
Necropsy - gross and microscopical examination of the tissues
Chemical-toxicological analysis - CHTA
Biological experiment - check suspected source of poisoning by experiment

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15
Q

Zinc phosphide is used as

A

rodenticide

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16
Q

Classification of rodenticides

A

Inorganic:
* Zinc phosphide
* Elemental phosphorus
* Thallium sulphate
* Oxide arsenite

Organic rodenticides:
* Coumarin rodenticides - warfarin and superwarfarin
* Fluoroacetates
* ANTU
* Alphachloralosa
* Endrin
* Bromethaline
* Cholecalciferol
* Compounds of plant origin

17
Q

Advantages of pyretroids

A
  • More effective at killing insects than pyrethrins
  • Used in low application concentrations
  • In natural ecosystems they undergo quick degradation mainly by soil microorganisms
18
Q

ANTU is a

A

rodenticide

19
Q

3 groups of symptoms in organophosphate poisoning

A
  1. Muscarinic
  2. Nicotinic
  3. CNS
20
Q

Nitrate stage occurs

A

3-7 hours after exposure

21
Q

Modes of penetration of insecticides (4)

A

Contact - do not penetrate to plant tissues
Systemic - penetrate by cuticle of plant cells
Peroral - by ingestion
Respiratory - kill pests through respiration

22
Q

What is the intoxication dose of H2S?

A

<1mg

23
Q

What are the stages of risk assesment (3)?

A
  1. Hazard identification
  2. Dose response evaluation
  3. Evaluation of exposure
24
Q

What is the colour of M1 and M2

A

Violet

25
Q

What is the purpose of acute oral toxicity test?

A

To find LD50 of a substance

26
Q

Normal and toxic values of urea

A

Normal = 2-7 mmol/L
Dubious = 8-12 mmol/L
Positive > 12 mmol/L

27
Q

After NO2 reacts with haemoglobin it is reduced to

A

NO-

28
Q

Which substance results in toxic utilization of urea?

A

Glutamine/glutamate

29
Q

What are Bromudioc and Flukmafen?

A

Rodenticides

30
Q

What is NaClO3 (sodium chlorate) used as?

A

herbicide