Deck 2 Flashcards

1
Q

Two groups of insecticides of which mechanism of action is inhibition of acetylcholinesterase

A

Organophosphate and carbamate aldicarb

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2
Q

Normal concentration of urea in milk is

A

2-7 mmol/L

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3
Q

PCB are determined by

A

Gas chromatography

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4
Q

Advantage of pyretroids

A
  • Human and environmental safety
  • High efficiancy - fastest knockdown
  • Multi crop - 3000 crops
  • Novel node of action - Na+ channel
  • Cost effective - 2-5 euro / hectar
  • Low dose - 5-15g active ingredient / hectar
  • Broad spectrum - chewing and sucking
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5
Q

ANTU is used as

A

rodenticide

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6
Q

Symptoms of organophosphate intoxication (groups), effect on nervous system

A

GIT - hypersalivation, abdominal spasms, diarrhea
Respiratory - bronchoconstriction, pulmonary edema, dyspnoea
Heart - bradycardia
Eye - miosis (excessive constriction of pupil)

Effect on nervous system
* Muscarinic - overstimulation of parasympathetic nervous system
* Nicotinic - ganglionic and myoneural junction stimulation (muscle fasciculation & weakness)
* CNS - nervousness, ataxia, apprehension, seizures, depression and convolution

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7
Q

Anticoccidicum monensin is determined by

A

TLC

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8
Q

Dinitrophenols act by

A

Inhibition of oxidative phosphorylation

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9
Q

Agents of methemoglobinaemia

A

Direct acting agents - nitrites, oxidase of nitrogen, potassium fericyanide, sodium chlorate, quinones, methylene-blue in large doses

Indirectly acting agents - aromatic nitro compounds and aromatic amino compounds

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10
Q

Mechanism of action, typical clinical symptoms and therapy of Zn3P2 intoxication

A
  • rodenticide
    Mechanism: acts in the acid environment of stomach or in contact with water. PH3 is released –> hydrogen phosphide poisoning

Clinical symptoms: abdominal pain, gas (tymphani of GIT), apathy, rigidity, vomiting, staggered moving, spasms and death (at high concentration)

Therapy: immediately after - gastric lavage, solution of copper sulphate or potassium permanganate

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11
Q

The characteristic clinical signs of DNOC poisoning

A

Ethiology: insecticide, herbicide and fungicide

Symptoms:
Yellow mucus membranes, skin and feathers. Hyperpnoea, dyspnoea, sweating, oliguria, muscle weakness, increased body temperature, spasms, rapid rigor mortis after death

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12
Q

The principal constituent of opium (10%) is

A

morphine

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13
Q

Treatment of urea intoxication includes the administration of

A

acetic acid, vinegar and hydrochloric acid

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14
Q

Ergotism is

A

a disease of farm animals that results from continuous ingestion of parasitic fungus - claviceps purpurea

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15
Q

Herbicide sodium chlorate causes when absorbed:

A

production of methemoglobin

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16
Q

Methylene blue dose …(?)

A

1-2 mg/kg

17
Q

Salt poisoning causes

A

disturbance of Na+ and water balance

18
Q

Amygdalin is

A

cyanogenic glycoside

19
Q

Thalium has been used as

A

rodenticide

20
Q

ANTU acts by

A

increasing permeability of lung capillaries and causes pulmonary edema

21
Q

Division of glycosides

A

Cardiac
Cyanogenic

22
Q

Sulphur and cyanide create

A

Rodenticides

23
Q

Antidote for zinc poisoning

A

Potassium permanganate
EDTA

24
Q

What is atropine

A

An alkaloid, which depresses the heart and CNS

25
Q

Characteristics of glycosides

A

Effect on heart and CNS

26
Q

What is the action of substances disturbing oxidative phosphorylation?

A

They disturb cellular respiration and energy supply

27
Q

Polarography characteristics

A

Qualitative and quantitative determination of Cl-, NO3-, Pb, Cu, Zn, Cd

28
Q

Pithomyces chartarum belongs to

A

Mycotoxins and causes facial eczema

29
Q

Elements of exposure

A

Acute exposure - accidental or occupational

Chronic exposure - intentional, occupational or environmental

30
Q

Influenze of chlorine

A

Bleaching and antiseptic effect