Deck 4

Question 1

What is pathogenesis of fever?

Answer 1

-Exogenous pyrogens –> produce fever through action of endogenous pyrogens, are released after initial stimulation of phagocytic cells.
Endogenous pyrogens cause fever -> stimulate hypothalamic prostaglandin .
Prostaglandin enter brain substance & active AMP thermostat in hypothalamus shifts up

Question 2

Effect of catecholamine in stress?

Answer 2

METABOLIC EFFECTS: increase glycogenesis in the liver -> hyperglycemia

ON CARDIOVASCULAR SYSTEM:
-increase heart rate
-vasoconstriction of resistant arterioles + increased blood pressure
-constriction of capacity & increase venous return
-vasoconstriction in skin & mucous membrane
-increase blood flow in heart, brain & skeletal muscles
-vasodilation of coronary arteria & arterioles

Question 3

Describe dysfunction during healing?

Answer 3

-hypovolemia = decrease blood volume –> constriction of B.V , less delivery of inflammation cells to site of injury
- anti-inflammatory cells
-insufficient nutrition during healing
-hypoxemic state –> decreasing of O2

Question 4

Dysfunction during reconstructive phase?

Answer 4

• cirrhosis of liver –> portal hypertension
• nutritional factors may interfere with production of collagen
• can be caused excessive production of collagen
• impaired contraction –> excessive wound contraction cause deformity

Question 5

Describe compensation of respiratory alkalosis?

Answer 5

• chemical buffering
• respiratory compensation
• renal correction