DD Topical Therapeutics in Derm

Question 1

Vehicle in dermatology

Answer 1

the substance in which the active ingredient is sitting in/delivered in

Question 2

What type of application/vehicle causes less allergy/sensitization?

Answer 2

Ointment

Question 3

Ointments

Answer 3

Water in oil emulsion

Question 4

Creams

Answer 4

Oil in water emulsion

Question 5

Gels

Answer 5

Semisolid emulsion in alcohol base

Question 6

Lotions/Solutions

Answer 6

Powder in water

Question 7

Foams

Answer 7

Pressurized collections of gaseous bubbles in a matrix of liquid film

Question 8

Potency of:
Ointments
Creams
Gels
Lotions/solns

Answer 8

Ointments - strong
Creams - moderate
Gels - strong
Lotions/solns - low

Question 9

1 gram of cream covers ________

Answer 9

1 gram of cream covers a 10cm x 10cm area of skin

-The rule of 10s

Question 10

1 gram of ointment goes ____ further than 1 gram of cream.

Answer 10

10%

-The rule of 10s

Question 11

FTU

Answer 11

• 1 FTU = 0.5 g

covers palm and back of hand.

or two palms

Question 12

Hydrocortisone

Answer 12

2.5%
"The Gentle Touch"
• Class 7, lowest potency
• Mild eczema in children 
• Good for face, intertriginous areas or groin

Question 13

Hydrocortisone adverse effects

Answer 13

• Skin atrophy with long-term use
• Telangiectasia:
• Striae formation: (stretch marks)

Question 14

Triamcinolone Acetonide

Answer 14

0.1% cream or ointment”The Almost All-Purpose Weapon”
• Class 4 - mid potency
• Available in many many sizes
• Effective against moderate spongiotic dermatoses
• Eczematous dermatitis, atopic dermatitis, allergic contact dermatitis, arthropod bites, id reactions, drug reactions
• Good for trunk and extremities

Question 15

Triamcinolone Acetonide adverse effects

Answer 15

• Long-term use is bad for facial, intertriginous and groin areas
• Leads to atrophy
• Steroid-induced rosacea

Question 16

active ingredient in ointment in cream or ointment delivers it stronger?

Answer 16

ointment

Question 17

Clobetasol Propionate

Answer 17

0.05% cream or ointment"Hercules"
• Class 1, super potent steroid
• Best in acute eruptions
	• Contact dermatitis
	• Acute drug eruptions

Question 18

Clobetasol Propionate adverse rxns

Answer 18

• Avoid the face, intertriginous areas, and groin because skin is thin.
  
  • Leads to atrophy
  • Steroid-induced rosacea
• Adrenal suppression
• Cushing’s syndrome
• Growth retardation
• NO MORE THAN 50g per week!