DD inflammatory skin disease Flashcards
Location: Stasis dermatitis Seborrheic dermatitis Atopic dermatitis Psoriasis
Stasis dermatitis - lower legs
Seborrheic dermatitis - scalp
Atopic dermatitis - flexor surfaces
Psoriasis - extensor surfaces
Etiology Stasis dermatitis Seborrheic dermatitis Atopic dermatitis Irritant dermatitis Allergic contact dermatitis
Stasis dermatitis - lower extremity edema
Seborrheic dermatitis - malassezia furfur
Atopic dermatitis - filaggrin
Irritant dermatitis - common irritant
Allergic contact dermatitis - common allergens
Misc facts
Atopic dermatitis
Allergic contact dermatitis
Psoriasis
Atopic dermatitis - associated with asthma and allergic rhinitis
Allergic contact dermatitis - delayed type hypersensitivity IV, confirmed with patch testing
Psoriasis - may be associated with increased risk of cardiovascular disease
Atopic dermatitits - common skin diseases associated with:
infants (birth-2 years)
□ Generalized eruption:
erythematous papules, redness, scaling and areas of lichenification
Atopic dermatitits - common skin diseases associated with childhood (2-12 years)
□ Involvement of flexural skin ® Antecubital fossa ® Popliteal fossa ® Neck ® Wrists ® Ankles
Atopic dermatitits - common skin diseases associated with:
Adult (>12 years)
□ Dry Skin (Xerosis)
□ Keratosis Pilaris
□ Ichthyosis vulgaris
□ Hyperlinearity of the palms
Atopic dermatitis diagnostic criteria
Must have: Itchy skin +Plus
• Three or more of the following:
o History of involvement of skin creases (or face if pt < 10 yrs)
o Personal history of asthma or hay fever (or FH of atopic disease if pt < 4 yrs)
o History of dry skin within the last year
o Visible flexural eczema (or face if pt < 4 yrs)
o Onset under 2 years of age
Most common type of contact dermatitis
Irritant Contact Dermatitis
Non-immunologically mediated rash
vs
Complex immune mediated rash
Non-immunologically mediated rash
- Irritant Contact Dermatitis
Complex immune mediated rash (type IV)
- Allergic Contact Dermatitis
- Drug eruptions
cellulitis vs allergic dermatitis
○ Cellulitis
- More painful/tender
- More In the dermis and subcu
- warm
- both sides can be affected, but more so unilateral involvement
○ Allergic dermatitis
§ More itchy
§ More epidermis
“psoriasis vulgaris” affects what % of pop? what triggers it?
- Affects 2% of the population (takes genetic disposition + environmental trigger)
5 main types of psoriasis:
- Plaque
- Gutatte
- Inverse (think intertriginous)
- Pustular
- Erythrodermic
Are nail changes associated with atopic dermatitis? Psoriasis?
No for atopic
yes for psoriasis
Auspitz sign
pinpoint bleeding upon scraping
- sign of psoriasis
Exanthemous drug eruptions
aka maculopapular eruptions aka morbilliform eruptions aka drug rashes
- Most common type of drug reaction in skin - Usually cell-mediated type IV hypersensitivity (just like contact dermatitis) - Drug Eruptions differential dx = Viral Exanthem (Viral infections enhance the risk of drug eruption)
