Day 2 (2): Obstruction of the Lacrimal Drainage System Flashcards

1
Q

Classification of Lacrimal Drainage System Obstruction

A
  1. Age of Onset: Congenital or Acquired
  2. Degree of Obstruction: Partial (Stenosis) or Complete
  3. Location
    - Upper system: Puncta, Canaliculi
    - Lower system: Lacrimal sac, NLD
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2
Q

Pertinent points in the history of CONGENITAL LS Obstructions

A
  1. CONSTANT tearing since BIRTH or shortly thereafter: COMPLETE blockage
    - upper system: minimal mucopurulent material
    - lower system: frequent mucopurulent material + matting or crusting of the eyelashes
  2. INTERMITTENT tearing with mucopurulence: PARTIAL blockage of lower system
    - e.g. swelling of inferior turbinate and mucosa with URTI or allergies
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3
Q

Pertinent points in the PE of Congenital LS Obstructions.

A

Reflex Tearing (Lacrimation) or Non-Obstructive Functional (Epiphora)

  1. Facial asymmetry, lagophthalmos: congenital CN 7 palsy –> paralysis of OO –> exposure keratopathy (lacrimation) + lacrimal pump failure (epiphora)
  2. Eyelid malpositions: ectropion, entropion
  3. Punctal position: medial
  4. Lash abnormalities: trichiasis
  5. Enlarged cornea + thinned sclera: buphthalmos
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4
Q

Pertinent points in the PE of Congenital LS Obstructions

A

Obstructive (Epiphora)

  1. Tear meniscus height
  2. (+/-) Puncta
  3. Matting of lashes +/- mucopurulent discharge
  4. Medial canthal mass
    - above MCT: tumor, nasofrontal encephalocele, anterior ethmoidal mucocele
    - below MCT: dacryocystocele
  5. (+/-) Retrograde discharge of mucoid material on firm palpation of lacrimal sac
  6. Fluorescein Dye Disappearance Test: children
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5
Q

Discuss punctal dysgenesis.

A
  1. Incomplete canalization with membranous occlusion of punctum
  2. Cause:
    - Failed dehiscence of epithelium overlying normal canaliculi
    - Failed canalization of most proximal canaliculi
  3. HX: Epiphora since birth or infancy
  4. PE: Translucent white membrane over punctum
  5. TX: Membranotomy with sharp punctal dilator
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6
Q

Discuss punctal agenesis

A
  1. Absence of punctum
  2. Cause: Failure of canaliculi outbudding from upper end of solid lacrimal cord
  3. HX: Epiphora since birth or infancy
  4. PE: (-) punctal papilla
  5. TX: Observe if minimal symptoms;
    Conjunctivodacryocystorhinostomy with Jones Tube if severe
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7
Q

Discuss canalicular dysgenesis and agenesis.

A

Agenesis: Failure of canaliculi outbudding from upper end of solid lacrimal cord

Dysgenesis: Incomplete canalization of cord

Symptoms dependent on severity and location of abnormality.

HX: Epiphora since birth or infancy
PE:
- agenesis: (-) punctal papilla
- dysgenesis: punctum ends blindly on probing
TX: Conjunctivodacryocystorhinostomy with Jones Tube (agenesis)

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8
Q

Most common etiology of congenital NLDO

A

Membranous obstruction at the valve of Hasner (between NLD and inferior turbinate)
- associated with premature birth

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9
Q

Pertinent HX and PE findings in Congenital NLDO

A

HX: Epiphora since birth or infancy + mucopurulent discharge and matting of eyelashes

PE:
1. Increased tear meniscus height
2. NEGATIVE fluorescein dye disappearance test: dye retention
3. Reflux of mucoid material upon firm pressure over the lacrimal sac

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10
Q

Interpretation of Fluorescein Dye Disappearance Test

A

POSITIVE FDDT
- dye coming out of nostrils
- PATENT lacrimal drainage

NEGATIVE FDDT
- dye retention
- OBSTRUCTED lacrimal drainage

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11
Q

Management of Congenital NLDO

A

Age: < 1 year old
- Conservative management
- 96% resolve spontaneously by the 1st year
- Erythromycin ointment + Crigler maneuver (lacrimal compression)

Age: > 1 year old
- Surgery: if still persistent
- Indications for EARLIER surgery:
1. Recurrent severe infection (dacryocystitis)
2. Dacryocystocele: proximal and distal block

Surgical Approaches:
1. NLD probing and irrigation
2. NLD intubation or balloon dacryoplasty
3. Dacryocystorhinostomy: create a new tear drainage system connecting the lacrimal sac and nasal cavity, bypassing the NLD

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12
Q

How does Crigler Maneuver or lacrimal sac compression work?

A

Digital compression of the lacrimal sac increases the hydrostatic pressure within the drainage system in an attempt to overcome the membranous obstruction of the distal end of the NLD

Remember: compress in a way that contents do no regurgitate from the puncta

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13
Q

What is a dacryocystocele?

A
  • Cystic lesion in the medial canthal area usually BELOW the MCT noted at birth or early in infancy
  • Contains trapped amniotic fluid and mucus produced by goblet cells in the lacrimal sac
  • Formed when a distal blockage (usually membranous) of the lacrimal sac causes distention of the sac, which also kinks and closes off the entrance to the common canaliculus
  • (+/-) intranasal component
  • 2 sites of blockage:
    1. Valve of Rosenmuller proximally (common canaliculi to lacrimal sac)
    2. Valve of Hasner distally (NLD to inferior meatus)
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14
Q

What are the pertinent HX, PE and MX of dacryocystocele?

A

HX: Bluish, cystic mass or swelling in the medial canthus at BIRTH (usually BELOW the horizontal midline)

PE: Bluish cystic well-circumscribed non-mobile mass below the MCT
- if BILATERAL: do Nasal exam to r/o INTRANASAL CYST
- may cause airway obstruction (because infants are nasal breathers)

MX:
1. Conservative:
- Crigler Maneuver (lacrimal sac compression)
- Topical antibiotics

  1. NLD Probing: indications
    - no resolution beyond 2 weeks of life
    - minimal improvement with compression
    - recurrent infection: allow inflammation to resolve first prior to doing surgery
    - signs of acute respiratory distress
  2. Marsupialization: for the intranasal cyst
  3. Dacryocystitis: systemic antibiotics

NOTE:
Decompression of an infected dacryocystocele with a skin incision should not be performed as this may cause a fistulous tract.

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15
Q

What are the common causes of ACQUIRED Punctal Stenosis (incomplete) or Occlusion (complete)

A
  1. Inflammation +/- Infection (Trachoma, Blepharitis)
  2. Allergic
  3. Chemotherapeutic agents: cicatrizing disease of the conjunctiva
  4. Tumors
  5. Iatrogenic injury
  6. Burn
  7. Traumatic
  8. Long-standing lid malposition
  9. Aging
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16
Q

Normal and stenotic punctal diameters

A

Normal: 0.2 mm to 0.5 mm
Stenotic: < 0.3 mm or inability to intubate with 26G cannula without dilation

17
Q

How is ACQUIRED Punctal Stenosis or Occlusion managed?

A
  1. Dilation with Bowman probe
  2. 3-snip Punctoplasty
  3. Mini-Monoka silicone stent intubation
18
Q

What are the common causes of ACQUIRED Canalicular Stenosis and Obstruction?

A
  • May involve the upper, lower or common canaliculus
  • similar to Acquired Punctal Stenosis or Occlusion
  1. Inflammatory +/- Infection
  2. Trauma
  3. Iatrogenic
  4. Tumors
  5. Medications (chemotherapeutic agents)
  6. Radiotherapy
19
Q

What are the pertinent things to note in the history and PE in cases of ACQUIRED Canalicular Stenosis and Obstruction?

A

HX:

  1. Onset and Duration of tearing
  2. (+/-) Discharge
  3. (+/-) Matting of eyelashes
  4. History of medication use
  5. History of eye infections, trauma, skin conditions
  6. Previous surgeries involving eye and surrounding area
  7. Comorbidities

PE:

  1. Increased tear meniscus height
  2. Canaliculitis: erythema, warmth, discharge
  3. Masses or skin lesions near medial lid
  4. Symblepharon:
    - adhesions between the palpebral and bulbar conjunctiva
    - evidence of past inflammation or infection of the conjunctiva
20
Q

What special tests can be done to check for canalicular stenosis and obstruction?

A
  1. Lacrimal Apparatus Irrigation:
    - complete upper/lower: reflux from SAME puncta
    - complete common: reflux from OPPOSITE puncta
    - partial/stenosis: reaches nasopharynx + SOME reflux
  2. Canalicular Probing:
    - (+) soft stop: membranous blockage
    - (+) grittiness: concretions or stones
21
Q

Management options for pts with canalicular stenosis and obstruction.

A
  1. Canaliculotomy
    - indication: canaliculitis, FB removal
    - incise 4 - 5 mm along the margin
  2. Canalicular Stenting/Mini-Monoka Intubation
    - indication: PARTIAL stenosis
    - mechanically dilates the canaliculus and prevents re-stenosis
    - kept in place for 3 - 4 months or longer
  3. Canalicular Trephination
    - indication: FOCAL DISTAL obstruction
    - hole created through the obstruction
  4. Canaliculo(dacryo)rhinostomy
    - indication: PROXIMAL canalicular obstruction at or beyond 8 mm from the punctum
    - excise the obstructed canaliculus and connect the patent canaliculus directly with the lacrimal sac or with the nasal mucosa
    - should have MINIMUM of 8 mm patent canaliculus
  5. Conjunctivodacryocystorhinostomy
    - creates a new pathway for tears through a Jones tube from the tear lake to the nasal mucosa
    - bypasses the entire lacrimal drainage system
    - for EXTENSIVE obstructions or with history of previous failed surgeries
    - treatment of choice for complete punctal and canalicular agenesis
22
Q

Canaliculorhinostomy vs Canaliculodacryorhinostomy?

A

CanaliculoRhinoStomy: obstructed canaliculus excised and patent canaliculus anastomosed directly to nasal mucosa (if WITHOUT FUNCTIONAL LACRIMAL SAC)

CanaliculoDacryoRhinoStomy: obstructed canaliculus excised and patent canaliculus with FUNCTIONAL LACRIMAL SAC anastomosed to nasal mucosa

Both followed by SILICONE INTUBATION.

23
Q

What is primary acquired nasolacrimal duct obstruction?

A
  • IDIOPATHIC involutional stenosis of the NLD
  • Cause unknown but with (+) inflammatory infiltrates and (+) edema –> compression of NLD
  • Females (longer and narrower canals) > Males
  • Middle-aged
  • Sequelae: Dacryocystitis d/t stasis of tears in the sac
24
Q

Pertinent findings in the HX and PE of pts with primary acquired NLDO.

A

HX:
1. Increased tearing: constant (complete) vs intermittent (incomplete)
2. Unilateral or Bilateral
3. Mucopurulent discharge
4. Medial canthal mass that doesn’t cross horizontal midline
5. If infected (dacryocystitis): erythema, warmth, pain, swelling

PE:
1. Increased tear meniscus height
2. Mucopurulent discharge with matting of eyelashes
3. Signs of inflammation: erythema, tenderness, warmth, swelling –> ACUTE
4. Crigler maneuver: compression of medial canthal mass causes reflux of mucoid or mucopurulent discharge –> CHRONIC
6. LAI:
- complete: reflux from OPPOSITE punctum
- incomplete: reflux from opposite punctum + passage to nose
7. Probing:
- hard stop (lacrimal bone): means obstruction is distal to the canaliculus and lacrimal sac
- if > 10 mm of probe inserted: in the lacrimal sac already

25
Q

What is the normal tear meniscus height?

A

Normal: 0.20 - 0.25 mm
Lacrimal drainage obstruction: 0.50 - 0.65 mm

Measured with Slit Lamp biomicroscopy

26
Q

Management of Primary Acquired NLDO

A

Dacryocystorhinostomy
- External or Endonasal approach
- if symptomatic and complete NLDO
- connection is created between the lacrimal sac and nasal cavity

If (+) Acute Dacryocystitis:
1. NO irrigation and NO probing
2. Antibiotics
- cover for S. aureus, S. pneumoniae and S. pyogenes)
- Co-Amoxiclav 625 mg TID or 1 g BID x 7 days
3. Warm compress
4. Pain meds
5. Abscess: I&D
6. Proceed with DCR once infection resolves

27
Q

Causes of Secondary Acquired NLDO

A
  1. Inflammatory +/- Infection
  2. Neoplastic (Primary/Secondary/Metastasis)
    - blood-tinged tears
    - painless, noncompressible solid mass extending ABOVE the MCT
  3. Traumatic
  4. Mechanical
  5. Iatrogenic
28
Q

When is surgery indicated for cases of lacrimal drainage system obstruction?

A
  1. Symptomatic
  2. Recurrent infections
29
Q

Basic tenet of surgery of lacrimal drainage system obstructions

A

Bypass area of obstruction and create a new passageway for tears to drain into nasal cavity