Data - Endocrine Flashcards
What is raised/lowered in primary hyperparathyroidism?
Calcium raised
Phosphate lowered
ALP and PTH raised
What is raised/lowered in primary hyperthyroidism?
Free thyroxine is raised
TSH is low/undetectable
What is raised/lowered in primary hypothyroidism?
Free thyroxine is low
TSH is raised
Synacthen test?
Stimulates adrenals to produce cortisol, response is lowered in Addison’s disease
Dexamethasone supression test?
Usually suppresses cortisol levels, via suppression of ACTH.
No suppression may indicate Cushing’s disease or syndrome, or an ectopic ACTH producing tumour
What is raised/lowered in secondary hyperthyroidism?
Free thyroxine is raised
TSH is also raised
What is raised/lowered in secondary hypothyroidism?
Free thyroxine is low
TSH is low
What is raised/lowered in secondary hyperparathyroidism?
Calcium lowered
Phosphate raised
ALP and PTH raised
Nail signs of Grave’s disease?
Thyroid acropachy - looks like clubbing
Periosteal hypertrophy of distal phalanges
Skin signs of diabetes?
Necrobiosis lipoidica - shins
Acanthosis nigricans - axillary
Hot, red swollen foot in diabetes?
Possibly Charcot’s arthropathy:
acute inflammation; fracture; bone thinning
Features of hypocalcaemia?
CATs go Numb: Convulsions Arrhythmias Tetany Numbness, feet, hands, mouth
Features of hypercalcaemia?
Stones (kidney) Bones (pains) Groans (abdo pain N+V) Thrones (polyuria--> dehydration) Psychic overtones (depression, anxiety, cognitive dysfunction)
Microvascular complications of diabetes?
Nephropathy
Retinopathy
Neuropathy
Macrovascular complications of diabetes?
Coronary artery disease
Peripheral artery disease
Stroke