Cytoskeletal Filaments

Question 1

Which filaments are polar? why?

Answer 1

microtubules and actin - because they have motor proteins that move cargo along them from + to - end and vice versa.

Question 2

What types of filaments are most cilia made of?

Answer 2

microtubules

Question 3

what filaments are muscle fibers made of?

Answer 3

actin

Question 4

what filaments are flagellar tails of sperm made of?

Answer 4

microtubules

Question 5

what filaments are mitotic spindles made of?

Answer 5

microtubules

Question 6

what filaments make up the contractile ring in dividing cells?

Answer 6

actin

Question 7

What is Pemphigus?

Answer 7

autoimmune disease in which antibodies disrupt the adhesion proteins that connect intermediate filaments that hold together skin

Question 8

kinesin

Answer 8

motor protein - walks towards the + or - end along the lattice of the microtubule.

Question 9

Myosin

Answer 9

motor protein - walks on actin, plus or minus end.

Question 10

Dyenin

Answer 10

motor protein -walks on microtubules towards the minus end.

Question 11

How do cilia and flagella move?

Answer 11

dyeing transiently binds to adjacent microtubule and walks down toward the anchored base (- end) causing it to bend. When dyenin then detaches, the cilia whip back

Question 12

Why does ciliary diskinesia cause situs inverses?

Answer 12

cilia do not move and therefore cannot direct the morphogen that creates L/R sides of the body embryonically to the left side, so it sometimes ends up on the right side. if on both or neither side - lethal