Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Clinical Pathology > Cytopathology of Epithelial Cells > Flashcards

Cytopathology of Epithelial Cells Flashcards

Dr. Short

1
Q

What are the characteristics of epithelial cells?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Type?

A

epithelial cells - “fried egg appearance”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Type?

A

cornified epithelial cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are characteristics of papillomas? Cytology?

A

Many types

Exophytic: classic papilloma, “wart”, cauliflower

Resemble normal squamous epithelial cells, may be large, ovoid to spindled

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Type?

A

papilloma (epithelial)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are characteristics of a sebaceous adenoma?

A

common - limbs, trunk, eyelids in dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What do sebaceous adenomas look like?

A

typically solitary, raise, smooth, or lobular “wartlike”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What do sebaceous adenomas look like on cytology?

A

cluster of well-differentiated spbocytes - abundant amount of vacuolated cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do you differentiate a sebaceous tumor from a papilloma?

A

SAs are more pedunculated and pink

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are sebaceous hyperplasias?

A

appear very much like SA, both visually and cytologically

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are sebaceous carcinomas?

A

uncommon, low-grade, locally invade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are perianal adenomas? Who is more commonly affected?

A

circumanal gland tumors. hepatoid gland tumors

typically older, intact males - likely androgen responsive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What do perianal gland tumors look like on cytology?

A

presence of cells that appear similar to hepatocytes: round, abundant, fine granular, pink-blue cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the apocrine gland tumors?

A
  • AGASACA
  • ceruminous gland (ear)
  • sweat gland adenomas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the characteristics of AGASACA? How does it appear?

A

Has neuro-endocrine tumor appearance but not officially of that cell type

Appears as mass affixed to anal sac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

AGASACA is malignant. What is it associated with?

A

hypercalcemia of malignancy → +/- renal disease

metastatic to lymph nodes and locally invasive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What does AGASACA cytology look like?

A

Clusters/sheets moderate sized cells, round nuclei with stippled chromatin, moderate pale cytoplasm, borders may not be distinct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are characteristics of cerunimous gland adenoma/adenocarcinoma?

A

most aural neoplasia is malignant

cystomatosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is this?

A

AGASACA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Pathology?

A

ceruminous gland adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are characteristics of sweat glands?

A
21
Q

What does a cutaneous follicular cysts and tumors look like?

A
22
Q

What are some basal cell tumors?

A

trichoblastoma
basal cell carcinoma

23
Q

What are trichoblastomas?

A

basal cell tumor

accounts for majority of basal cell tumors | single, firm, elevated intradermal mass, benign

24
Q

What are basal cell carcinomas?

A

exhibit many COM, lots of mitotic figures

25
Q

What is the difference between trichoblastomas and basal cell carcinomas?

A

t: benign
bcc: malignant

26
Q

What are characteristics of squamous cell carcinomas?

A

can occur anywhere in the skin, places with sun damage

27
Q

What are characters of squamous cell carcinoma on cytology?

A
  • COM
  • asynchronous nucleus to cytoplasm
  • often see neutrophilic inflammation
    etc
28
Q

Pathology?

A

squamous cell carcinoma

29
Q

Pathology?

A

squamous cell carcinoma - reptile

30
Q

What are the types of visceral epithelial tumors?

A
31
Q

What species are pulmonary tumors more common in?

A

cats - most feline tumors metastasize

32
Q

What are characteristics of pulmonary tumors on cytology?

A

ciliated columnar epithelium = bronchoalveolar origin

33
Q

Origin?

A

pulmonary tumors

34
Q

What are the characteristics of thymomas?

A

mostly older dogs and cats

small lymphocytes predominant cells

epithelial with COM

35
Q

Tumor? What origin?

A

thymoma - epithelial

36
Q

What are the characteristics of hepatocellular adenoma?

A

usually single mass of one lobe

37
Q

What are the characteristics of hepatocellular adenocarcinoma?

A

3 forms: massive, nodular, diffuse

well-differentiated can look benign

38
Q

Type - cell line?

A

hepatocellular - epithelial

39
Q

What are characteristics of coholangiocellular carcinomas?

A

most common primary hepatic tumor of cats - may cause cholestasis

aspiration yield cellular aspirates

cuboidal cells with scant cytoplasm, well-differentiated

40
Q

What are characteristics of biliary adenomas, cholangiocellular adenomas, and cyst adenomas?

A

very rare, may present as multiple nodules on multiple lines and may cause cholestasis

solitary, circumscribed lesions with small cysts

41
Q

What are characteristics of exocrine pancreatic adenocarcinoma?

A

usually solitary mass/nodule

neutrophilia, high pancreatic enzymes, elevated ALT/ALP, highly cellular

42
Q

What are gastrointestinal epithelial tumors?

A

esophagus, stomach, intestine

43
Q

Look at this

A
43
Q

What are epithelial tumors in the esophagus?

A

primary neoplasia is rare
SCC arises from esophageal muscle epithelium

44
Q

Contrast species differences with transitional cell carcinoma location

A

Dogs: trigone region

Cats: bladder wall opposite trigone

45
Q

What is characteristic on cytology for transitional cell carcinoma?

A

COM, Melamed-Wolinska bodies

46
Q

Look at characteristics of mammary glands

A

mostly in caudal glands

47
Q

What are the types of neuroendocrine tumors?

A
48
Q

What are the effects of an insulinoma?

A

hypoglycemia: tumor is secreting large amounts of insulin

insulinoma

49
Q

What happens with a pheochromocytoma?

A

large amounts of catecholamine release

Clinical Pathology (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions