Cytology Flashcards
What are the 4 basic tissues?
Epithelium
Connective Tissue
Muscle
Nerve
Exocrine glands and endocrine glands are formed from what type of tissue?
Epithelial
What are the 3 shapes of epithelial cells?
Squamous
Cuboidal
Columnar
Select the functions of epithelial cells -
Absorption
protection
secretion
excretion
gas exchange
All of the above
Connective tissue is - non-vascular/vascular?
Vascular
List some of the functions of Connective Tissue -
- Serves as a medium in which blood vessesl distribute nutrients and take up metabolic waste
- Involved in immune & inflammatory responses
- Involved in tissue repair following injury
What type of tissue is responsible for movement and changes in size and shape of body organs?
Muscle
What are the myofilaments that occupy most of the muscle cytoplasm?
Actin and myosin
What are the 2 main nervous system cells?
neuron and supportin cells
T/F
Tissue cells can be membrane bound and non-membrane bound
True
What are the 3 major components of the Nucleus?
Nuclear Envelope
Chromatin
Nucleolus
What are the main components of the Nuclear Envelope?
Outer membrane
Inner membrane
Niclear pores
Nuclear lamina
List the morphology of a nucleus in “normal cells”
Shape
Size
Number per cell
Location
- Shape: round, ellipsoid, infolded, lobulated
- Size: varies
- Number Per Cell: none to multie
- Location: central, basal, eccentric
How much space seperates the 2 unit membrane of the nucleus?
10-30nm
What other organelle is the outer membrane of the nuclear envelope continuous with?
Why are tehre no ribosomes on the outer membrane?
rER
Psyche - the outer membrane can have ribosomes on it.
T/F
The inner membrane of the nucleus is associated with the nuclear lamina and is supported by chromatin…
- False
- The inner membrane is supported by the lamina and can be associated with chromatin
What are the uni-directional gates of the nucleus?
- There are none
- Nuclear pores are the bidirectional gates of the nucleus
What are the two methods that molecules can pass through the Nuclear Pores?
- Small molecules (<40-60 kd) can diffuse through
- Any size proteins with a nuclear localization amino acid sequence can be transported in via active transport
What is required of a protein to be facilitatively transported into the nucleus?
- Nuclear localization amino acid sequence
- Also - it is not transported through facilitated transports - it is thorugh active transport.
What is another name for nuclear pores?
Nucleoporins
Functions of the Nuclear Lamina:
- Gives [] and [] to the nuclear envelope
- Organizes the [] nuclues (mitotic phase)
- Structural link between [] and the nuclear envelope
- Responsible for the dissolution and [] of the nuclear envelope during [] []
- Positions [] [] complexes within the nuclear evnelope
- shape and stability
- interphase
- chromatin
- reformation, cell division
- nuclear pore
Where is the nuclear lamina generally located?
Between the inner nuclear membrane and the peripheral heterochromatin
What type of proteins make up the Nuclear Lamina?
intermediate filament proteins called lamins
What activity causes the lamina to break apart during mitosis?
lamin phosphorylation