Cytokines Available in Recombinant Form

Question 1

Clinical use of Aldesleukin?

Answer 1

(IL-2)

↑ lymphocyte differentiation and ↑ NKs - used in renal cancer and metastatic melanoma

Question 2

Clinical use of Interleukin-11?

Answer 2

↑ platelet formation - used in thrombocytopenia

Question 3

Clinical use of Filgrastim?

Answer 3

(G-CSF)

↑ granulocytes - used for marrow recovery

Question 4

Clinical use of Sargramostim?

Answer 4

(GM-CSF)

↑ granulocytes and macrophages - used for marrow recovery

Question 5

Clinical use of Erythropoietin?

Answer 5

Anemias, especially associated with renal failure

Question 6

Clinical use of Thrombopoietin?

Answer 6

thrombocytopenia

Question 7

Clinical use of Interferon-α?

Answer 7

Hep B and C, leukemias, melanoma

Question 8

Clinical use of Interferon-β?

Answer 8

MS

Question 9

Clinical use of Interferon-γ?

Answer 9

Chronic granulomatous disease → ↑ TNF