CV Adrenaline (Epinephrine's)

Question 1

What are the common indications for Adrenaline?

Answer 1

1. Cardiac arrest in ALS treatment algorithm
2. Anaphylaxis
3. Used during endoscopy as vasoconstriction
4. Prolong anaesthesia

Question 2

What is the mode of action for adrenaline?

Answer 2

1. Agonists of alpha 1,2 beta 1,2 adrenoreceptors: fight/flight
2. Vasoconstriction of vessels supplying skin: alpha 1
3. Inc HR, vasodilation of vessels supplying heart: Beta1
4. Broncodilation and suppression of mast cells

Question 3

What are the important adverse effects of Adrenaline?

Answer 3

1. In cardiac arrest, followed hypertension
2. Anxiety, headaches, tremor, palpitation
3. May cause angina, MI and arrythmias

Question 4

What is an important warning concerning Adrenaline?

Answer 4

Where patients receiving beta blockers also, adrenaline may induce widespread Vasoconstriction, since not opposed by beta2 mediated vasodilation.

Question 5

How is adrenaline PX?

Answer 5

In life threatening conditions it is administered first then prescribed

Question 6

In cardiac arrest?

Answer 6

Prefilled syringe: 1:10000 (1mg in 10 ml)