Cuntaneous Fungal Infections Flashcards
objectives of self treatment of fungal infections
provide symptomatic relief
eradicate existin infection
prevent future recurrent infections
refer if infection widespread, systemic, recurrent, or persistent
activity of clotrimazole or miconazole what they are used for
fungistatic with broad spectrum of activity to treat dermatophyte and yeast infections
application of clotrimazole or miconazole
thin layer morning and evening
adverse effects of clot and micon
local skin irritation
hypersensitivity
preparations of imadazole or azoles available in canada
clotrimazole- cream
miconazole- cream, spray, powder
activity of tolnaftate and uses
narrow spectrum antifungal
only for dermatophyte infectiosn
application of tolnaftate
apply mornign and evenign
adverse effects of tolnaftate
local skin irritation
activity and uses of undecylenic acid
unknown
used for dermatophyte infections
application adn adverse effects of undecylenic acid
twice daily
itching, burning, stinging
activity of nystatin and uses
fungistatic or cidal
only for candidal infections
application and adverse effects of nystatin
2-3 times daily
rarely irritation
activity of ciclopirox
antimycotic agent
effective against dermatophytes, yeast, and some bacteria
application and adverse effects of topical ciclopirox
itch, burn, red
apply twice daily for 4 weeks
time of effects for topical ciclopirox
first week relief of itchign and other symptoms
reevalute if not improvement after 2 weeks
two types of ciclopirox
loprox- 1%cream/lotion
stieprox 1.5% shampoo 2-3 times per week for seborrheic dermatitis
activity of terbinafine
fungicidal to dermatophytes
fungistatic to candida
application adn adverse effects of topical terbinafine
once daily for one week
itch, burn, rash, dryness
uses of oral terbinafine
fungal nail infections
severe tinea skin infections failed with topical
adverse effects of oral terbinafine
interfere with cytp450 so hepatic failure, gi disturbances, rash, headache
ketaconazole activity
broad spectrum
oral ketoconazole adverse effects
fatal liver toxicity so only for life threatening infections
why are dermatophytes restricted to scalp, nails, and superficial skin
requires keratin for growth/proliferation
how are dermatophytes spread
contact with infected person, soil, animal, indirectly from fomites