CUCI Flashcards

1
Q

Predisposicion genetica para CUCI?

A

HLA 2 y DR2, BW35

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2
Q

Macroscopicos:

A

confinada a la mucosa y submucosa
Afecta al recto sigmoides 40-50%
Pancolitis 20%
Lesiones continuas

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3
Q

A que tipo de cancer se relaciona el CUCI?

A

riesgo alto de ca de colon

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4
Q

Microscopicamente que se observa en CUCI

A

ulceras superficiales ertitematosa, edema, superficie granular fina, pseudopolipos
Puede formar abscesos cripticos

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5
Q

Complicacion mas grave en CUCI

A

Megacolon toxico (perdida de austras)

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6
Q

Clinica de CUCI

A

diarrea cronica con sangre

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7
Q

Labs que encontramos en un px con CUCI

A

anemia, aumenta VSG y PCR

P ANCA

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8
Q

Manifestaciones extra intestinales en CUCI

A

-pioderma gangrenoso
Epiescreritis o conjuntivitis
Esteatosis hepatica

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9
Q

Tx por etapas de CUCI

A

Leve/moderado: Mesalamina, si no mejora: metronidazol o ciprofloxacino
Grave: corticoides, prednisona , si no mejora: inmunosupresores: MTX, sulfazalacina

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