CSF Flashcards
ventricle connections
interventricular foramen (btwn lateral and 3rd - 2 of them)cerebral aqueduct (btwn 3rd and 4th - 1)
CSF exit sites
all 3 in 4th ventricle2 foramen of Lushka (lateral)1 foramen of Magendie (medial)
choroid plexus
on at least 1 wall of all ventriclesproduce CSF
CSF circulation
- made through choroid plexus2. CSF from lateral/3rd through cerebral aqueduct3. exit through 4th ventricle foramens4. circulate in subarachnoid space5. drain through arachnoid villi into dural venous sinuses
space vs production
90 - 150 cc space400 - 500 cc produced daily
CSF qualities
P: 60 - 170 mmH20color: clear or yellowish, pH: 7.33 (little more acidic than art blood)conc: less glucose, much less protein, isotonic w/ serumcells: very few WBCs, no RBCs
hydrocephalus mech
increase in CSF vol may lead to dilation of 1+ ventricles
communicating hydrocephalus mechanism
impaired CSF absorption @ arachnoid granulations or tumor in subarachnoid space that limits CSF flow–> more vol in ventricles and in subarachnoid space
normal pressure hydrocephalus mechanism
type of communicating hydrocephalus common in elderlydue to calcifications of arachnoid granulations
normal pressure hudrocephalus
wacky, wet, wobblymental decline, urinary incontinence, abnormal gait (apraxic)
apraxic gait
shuffling like feet are stuck to the floor
non-communicating hydrocephalus mech
obstruction to CSF flow in ventricular system (blockage)
sites of blockage for non-communicating hydrocephalus
interventricular foramen, foramen of Lushka/Magendie*cerebral aqueduct (infants)
hydrocephalus ex vacuo
increase in ventricular size and increase in volume of CSF after a loss of brain tissuenormal CSF P
arteries into brain
internal carotids (anterior)vertebral arteries (posterior) (through transverse foramina)
