CSF Flashcards
what supplies the dura with blood
middle meningeal artery spreads out between the layers
what is the dura innervated by
anterior 2/3 CN 5
post 1/3 CN 10
where is CSF produced
in the choroid plexus which is the blood vessels 4 ventricles
what sort of cells line the ventricles and what do they do
ependymal - ciliated-epithelial glial cells - clear waste, sort out the nutrition
how does the CSF get out of the choroid plexus
fenestrated capillaries
how does the CSF get moved upwards in the head
diastole - pressure differential
how does the CSF get into the sup saggital sinus
absorbed there by arachnoid granulations
where can CSF get blocked and what’s the treatment
cerebral aqueduct - obstructive hydrocephalus - shunt
what forms BBB
feet of astrocytes`
why do antibiotics work in meningitis
meningitis has already compromised BBB
what CAN cross the BBB
anything lipophilic - eg opioids
where in the head is there no BBB
blood vessels in subarachnoid space
what do you need to watch for after meningitis
bbb can take a long time to recover
what is the relationship between gut microbiome and bbb
gut dysbiosis can increase permeability of bbb. bad
