corticosteroids and anabolic steroids Flashcards

1
Q

what is steroids ?

A

organic compounds characterised by a specific molecular structure consist of 4 interconnected carbon rings ( man made hormones )

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2
Q

steroids can be categorised into its function.

A
  • corticosteroids ( adrenal gland )
  • anabolic steroid ( testes )
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3
Q

what types of steroids in body ?

A
  • anabolic
  • corticosteroids
  • sex hormones
  • vitamin D
  • cholesterol
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4
Q

what is function and medical use of corticosteroids?

A

function : reducing inflammation and modulate immune response
medical use : reduce inflammation and suppress immune response in autoimmune conditions

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5
Q

what is properties of corticosteroids

A
  • glucocorticoid
    regulate inflammation and immune response
  • mineralocorticoids
    regulate electrolyte and fluid balance
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6
Q

why inflammation occur ?

A

body initiates in response to harmful stimuli such as pathogen , damage cell or irritants

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7
Q

what is symptoms of inflammation?

A
  • redness
  • heat
  • swelling
  • pain
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8
Q

what main role of inflammation?

A

as body defense mechanisms that help to protect and heal tissue

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9
Q

state acute inflammation

A
  • allergic reaction
  • infection
  • burns
  • trauma injury
  • cuts , wounds
  • frostbite
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10
Q

state chronic inflammation

A
  • cardiovascular disease
  • rheumatoid disease
  • neurological disease
  • lupus
  • autoimmune diseases
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11
Q

example of corticosteroids based on formulations and indications

A

oral
asthma / crohn diseases/ allergy / MS / cancers
- prednisolone
- hydrocortisone ( low potency in creams )
- dexamethasone
- methylprednisolone

injections
joint inflammation , RA
- prednisolone
-hydrocortisone
-dexametahasone
- fludrocortisone
- methylprednisolone
- triamcinolone

topical
nasal sprays ( allergic rhinitis)
- budesonide
- beclomethasone
- mometasone
- fluticasone

eye / ear drop ( swelling and inflammation)
- betamethasone ( high potency in cream )
- hydrocortisone
- dexamethasone

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12
Q

what is the side effect of corticosteroids in systemic ?

A
  • cushing syndrome
  • GI irritant
  • indigestion
  • heartburn
  • weight gain
  • difficulty sleeping
  • diabetes
  • osteoporosis
  • hypertension
  • glaucoma and cataracts
  • mental health
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13
Q

what is side effects of corticosteroids when applied to skin

A
  • thinning skin
  • permanent stretchmarks
  • allergic contact dermatitis
  • acne
  • hair growth at site of application

in eyes or ear
- dryness
- irritation

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14
Q

what is anabolic steroids?

A

synthetic substances that mimic effects of male sex hormone testosterone

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15
Q

what is function of anabolic steroids?

A

promotes tissue and muscle growth and promote development of male sexual characteristics

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16
Q

for medical use

A

treat conditions cause muscle wasting or severe weight loss due to certain diseases

17
Q

state example drug of anabolic steroid

A
  • testosterone
  • nandrolone
  • stanozolol
  • oxandrolone
  • methandrostenolone
  • trenbolone
  • boldenone
  • methenolone
18
Q

what is properties of anabolic and androgenic ?

A

anabolic : promotion of tissue and muscle growth and maintains bone density

effect
- increased muscle growth and strength
- enhanced recovery after physical exertion
- reduce fatigue

androgenic : development and maintenance of make characteristic

effect
- deepening of voice
- facial and body hair growth
- increased libido

19
Q

who can misuse of anabolic steroids?

A
  • bodybuilder who are involved in competitive sport
    -young people who are insecure with their body image and want to look muscular