cortical lesions Flashcards
Frontal lobe in human cognition
Voluntary movement, language fluency (L side), motor prosody (R side), comportment, executive function, and motivation.
Parietal lobe in human cognition
tactile sensation, visuospatial function (R), Attention (R), Reading (L), Writing (L), Calculation (L).
Temporal lobe in human cognition
language comprehension (L), sensory prosody (R), Memory, emotion.
Occipital lobe in human cognition
vision, visual perception, visual recognition.
The 3 major frontal lobe syndromes
- disinhibition
- executive dysfunction
- apathy
Disinhibition lesion locations
orbitofrontal lesions
disinhibition is a disorder of
comportment when a person can no longer adequately integrate limbic drives into appropriate behavioral repertoire.
disinhibition signs
- Irritability
- loss of empathy
- impulsivity
- hypersexuality
- hyperphagia
- violence.
Executive dysfunction location of lesions
dorsolateral prefrontal lesions
Executive dysfunction signs
- no longer have capacity to plan, carry out and monitor sequential goal directed action
- lack preservation
- altering actions in response to changing environmental stimuli
apathy lesion located
medial frontal lesion
apathy signs
- lack of motivation
2. most severe forms are abulia and akinetic mutism
Major Cognitive disorders related to temporal lobe lesions
- wernicke’s aphasia
- sensory aprosody
- amnesia and memory
- emotion
Wernicke’s Aphasia:
auditory comprehension is impaired because of a lesion n post. region of L superior temporal gyrus
(Wernicke’s area, Brodmann area 22).
Sensory aprosody:
diminished ability to comprehend emotional inflection of speech due to lesion in R hemisphere analogue of Wernicke’s area.
Amnesia and memory
hippocampus is essential for new learning. Only remove 1 hippocampus not both during surgery.
Emotion disorder from temporal lobe lesion
basic emotions of flight/fight, feeding, and sexuality as mediated by limbic system from connections between temporal lobe and diencephalon.
Temporal lobe epilepsy:
temporolimbic lesion of temporocortical region affecting emotion.
Commonly caused by epilepsy lesions in the brain causing lasting personality changes and a deepened emotionality.
Hemineglect
failure to report, respond to, or orient to sensory stimuli that can not be explained by primary sensory dysfunction.
Inattention to one side of the body or extrapersonal space.
hemineglect is common after
lesion to R hemisphere (dominant for attention).
L hemineglect:
disabling disorder of cognition.
Occipitoparietal
dorsal stream, tells “where” in visual system
Occipitotemporal
ventral stream, tells “what” something is in the visual stream.
Visual field deficits
absence of vision!!!
So actually UNABLE to physically see something.