Chemosensation Flashcards
Ageusia:
loss of taste
Anosmia
loss of smell
test smell
scratch and sniff test
taste test
Patients react to different chemical concentrations in taste testing; this may involve a simple “sip, spit, and rinse” test, or chemicals may be applied directly to specific areas of the tongue.
Simple chemosensation test
In clinic, 2/3 of people will complain of loss of taste.
However, once you actually check for loss of taste, instead, 90% have actually lost or reduced their sense of smell.
Smell: Receptor cell =
ciliated bipolar neuron innervated by CN I w/ olfactory bulb as primary sensory nucleus.
Taste: Receptor cell =
- modified epithelial cell that synapses onto nerve fiber from cranial ganaglion cell to CN VII, IX, X.
- The primary CNS nucleus is the NST.
Chemisthesis: Receptor cell:
- free nerve ending of cranial ganglion cell innervated by CNV.
- Detection of irritant chemicals by trigeminal nerve endings.
- Primary sensory nucleus is Spinal Trigeminal Nucleus.
Ortho-nasal =
actually through your nostrils.
Retro-nasal =
through your mouth traveling through the concha to get to the olfactory epithelium.
CN 3 exits midbrain at
interpeducular cistern
CN 4 exits midbrain
dorsally, just below inferior colliculus (note it originates in contralateral midbrain and crosses before it exits the brainstem)
CN 5 enters/exits
the lateral pons. fibers traverse middle cerebellar peduncle
CN 6 exits
medially at the ponto-medullary junction
CN 7/8 exit and enter respectively
at cerebello-pontine angle
CN 9/10 exit
the lateral medulla (between olive and inferior cerebellar peduncle)
CN 11 originates
From c1-c5 segments of spinal cord
CN 11 exits
the spinal cord laterally–in between the dorsal and ventral rootlets.
CN 12 exits
medulla between olive and pyramid.
Secondary gustatory cortex is located
in the orbitofrtonal surface
areas.
Secondary gustatory cortex receives projections from
- the primary gustatory area located on the interior insula
2. olfactory insula
Orbitofrontal cortex:
where integration of taste and smell leads to perception of FLAVOR!!!