Coronary Artery Disease

Question 1

What is the major cause of Coronary Artery Disease?

Answer 1

atherosclerosis.

Question 2

Coronary Artery Disease risk factors

Answer 2

Nonmodifiable Risk Factors
age
white
female
family history

Modifiable Risk Factors
Blood pressure (BP) ≥140/90 mm Hg
Diabetes
Tobacco use
Physical inactivity
Obesity:

Question 3

4 stages of development in atherosclerosis are

Answer 3

A, Damaged endothelium.

• cause a local inflammatory response
• vulnerability to lipid deposits

B, Fatty streak and lipid core formation.
-cholesterol/lipds deposited

C, Fibrous plaque.
-collagen covers the fat

D, Complicated lesion

• plaque ruptures
• thrombus forms
• increase narrowing

E . Collateral circulation
-Arterial anastomosis

Question 4

Clinical manifestations include

Answer 4

angina, pressure, squeezing, burning, dyspnea, and edema.

Question 5

Coronary Artery Disease Health promotion

Answer 5

Physical activity
• FITT formula: 30 minutes on most days of the week
• Regular physical activity contributes to
weight reduction.
• reduction of systolic BP.
• in some men more than women, increase in HDL cholesterol.

Nutritional therapy
• Therapeutic lifestyle changes
• Omega-3 fatty acids
• lowering LDL cholesterol.
• decreased intakes of saturated fat and cholesterol
• increased intakes of complex carbohydrates (eg, whole grains, fruit, and vegetables) and fiber.

Reduce stress, tobacco

Question 6

Coronary Artery Disease Drugs

Answer 6

Cholesterol-lowering drug therapy

Antiplatelet therapy