Coordinating the Immune Response to Infection Flashcards
1
Q
Which cells interact with T lymphocytes to coordinate the adaptive immune response?
A
Dendritic cells
2
Q
Dendritic cells enter the Lymph node by which lymph?
A
Afferent lymph
3
Q
How do T Lymphocytes survey target cells? How do they know which cells to target?
A
T lymphocytes target cells via a cell migratory process, using integrins and chemokines.
Inflammation increases expression integrin ligands, and increases the strength of adhesion with activated T cells
4
Q
Which cytokine is response for a T Lymphocyte in gaining effector function?
A
Interleukin-2
5
Q
Cytotoxic T cell kill via the secretion of two things - what are they?
A
Perforin
Granzyme
6
Q
What are the two types of T Helper cells?
A
Th1
Th2
