Contraindications and Side effects for anti-arrhythmics

Question 1

Contra-indications for fleicainide and propafenone (Class IC)

Answer 1

Ischemic heart disease and structural heart disease

Question 2

Contra-indications for sotalol (Class III)

Answer 2

Significant LV dysfunction

Question 3

Contra-indications for dofetilide (Class III)

Answer 3

None

Question 4

Contra-indications for dronedarone (Class III)

Answer 4

Decompensated heart failure, permanent AF

Question 5

Contra-indications for amiodarone (Class III)

Answer 5

None

Question 6

Side effects for flecainide and propafenone

Answer 6

bradycardia, fatigue, metallic taste

Question 7

Side effects for sotalol

Answer 7

bradycardia, fatigue, QT prolonging, avoid other QT prolonging drugs, needs inpatient load

Question 8

Side effects for dofetilide

Answer 8

QT prolonging, avoid other QT prolonging drugs, needs inpatient load

Question 9

Side effects for dronedarone

Answer 9

Diarrhea, nausea, abd pain, rare liver toxicity, mild QT prolongning, mild renal dysfunction

Question 10

Side effects for amiodarone

Answer 10

neuropathy, tremor, night terrors, hepatitis (rare), nausesa, photosensitivity, discoloration, pulmonary fibrosis, hyper/hypothyroid disease, optic neuritis, corneal deposits