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Cardiology > Autonomic Drugs > Flashcards

Autonomic Drugs Flashcards

1
Q

The parasympathetic system causes which of the following properties: Secretion, SM contraction, SM relaxation, SA/AV node

A

Positively stimulates Secretion and SM contraction

Negatively affects/inhibits SA/AV node

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2
Q

The sympathetic system affects which of the following properties: Secretion, SM contraction, SM relaxation, SA/AV node

A

Positively stimulates SM contraction, SM relaxation, SA/AV node

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3
Q

What are some of the sympathetic receptors?

A

a1, a2, B1, B2

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4
Q

What are some of the parasympathetic receptors?

A

M2 and M3

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5
Q

What are the PARAsympathetic receptors for the eye, salivary glands, heart, lungs, stomach, bladder?

A 
Eye: M3
Salivary Glands: M3
Heart: M2
Lungs: M3
Stomach: M3
Bladder: M3
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6
Q

What are the SYMpathetic receptors for the eye, salivary glands, heart, lungs, stomach, bladder?

A 
Eye: a1, B2
Salivary Glands: B2
Heart: B1
Lungs: B2
Stomach: B2
Bladder: a1, B2
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7
Q

M3 receptor stimulation has what effects on Secretion, SM contraction, SM relaxation, SA/AV node

A

Secretion: Stimulates
SM Contraction: Stimulates
SM relaxation: No effect
SA/AV node: No effect

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8
Q

M2 receptor stimulation has what effects on Secretion, SM contraction, SM relaxation, SA/AV node

A

Secretion: No effect
SM Contraction: No effect
SM relaxation: No effect
SA/AV node: Inhibits

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9
Q

a1 receptor stimulation has what effects on Secretion, SM contraction, SM relaxation, SA/AV node

A

Secretion: No effect
SM Contraction: Stimulates
SM relaxation: No effect
SA/AV node: No effect

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10
Q

a2 receptor stimulation has what effects on Secretion, SM contraction, SM relaxation, SA/AV node

A

Secretion: No effect
SM Contraction: stimulates?
SM relaxation: No effect
SA/AV node: No effect

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11
Q

B1 receptor stimulation has what effects on Secretion, SM contraction, SM relaxation, SA/AV node

A

Secretion: No effect
SM Contraction: No effect
SM relaxation: No effect
SA/AV node: Stimulates

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12
Q

B2 receptor stimulation has what effects on Secretion, SM contraction, SM relaxation, SA/AV node

A

Secretion: No effect
SM Contraction: No effect
SM relaxation: Stimulates
SA/AV node: No effect

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13
Q

a1, a2, B1, B2 stimulates which type of G-protein?

A

a1: Gq
a2: Gi
B1: Gs
B2: Gs

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14
Q

M2 and M3 stimulates which type of G-protein?

A

M2: Gi
M3: Gq

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15
Q

Atropine and Glycopyrrolate act on which receptor/? Are they agonists or antagonists?

A

M2 antagonists, thus increasing cardiac output/HR

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16
Q

Dobutamine and isoproternol are what type of drugs?

A

B1 agonists, thus increasing cardiac output/contractility

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17
Q

Metoprolol, carvedilol, and nadolol are what type of drug?

A

B-1 antagonists,thus decreasing cardiac output

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18
Q

M3 activation on the lungs causes bronchoconstriction or bronchodilation?

A

bronchoconstriction

19
Q

B2 activation on the lungs causes bronchoconstriction or bronchodilation

A

bronchodilation

20
Q

Methacholine is what kind of drug?

A

M3 agonist, thus causing bronchoconstriction

21
Q

Ipratropium, tiotropium,, glycopyrrolate are what type of drug?

A

M3 antagonists, thus causing bronchodilation

22
Q

Albulterol, salmeterol, epinephrine are what type of drugs?

A

B2 agonists, thus causing bronchodilation

23
Q

Detrusor muscle contraction is caused by stimulation of which receptor?

A

M3, thus promoting urination

24
Q

Detrusor relaxation is caused by stimulation of which receptor?

A

B2, thus inhibiting urination

25
Q

Urethral contraction is caused by which receptor?

A

a1, thus inhibiting urination

26
Q

Bethanachol is what kind of drug?

A

M3 agonists, thus promoting urination

27
Q

Oxybutynin, solifenacin, tolterodine is what kind of drug?

A

M3 antagonists, thus inhibiting urination

28
Q

terazosin, doxazosin, and tamsulosin are what kind of drug?

A

a1 antagonists, thus promoting urination

29
Q

Stimulation of the M3 receptor would have what effect on the GI system?

A

It would induce SM contraction thus promoting digestion

30
Q

Stimulation of the B2 receptor would have what effect on the GI system?

A

It would induce SM relaxation thus inhibting digestion

31
Q

Dicyclomine and Hyocyamine are what type of drugs?

A

M3 antagonists, thus reducing peristalsis

32
Q

Stimulation of the M3 receptor has what effect on saliva?

A

Causes watery saliva secretion

33
Q

Stimulation of the B2 has what effect on saliva?

A

Thick saliva secretion

34
Q

Pilocarpine is what kind of drug?

A

M3 agonist, thus promoting watery saliva secretion

35
Q

Glycopyrrolate is what kind of drug?

A

M3 antagonist, thus causing THICK saliva secretion

36
Q

Stimulation of the a1 receptor has what effect on the eyes?

A

Affects the Dilator muscle, thus causing smooth muscle contraction leading to more light in the eyes

37
Q

Stimulation of the M3 receptor has what effect on the eyes?

A

Affects the constrictor muscle, thus causing contraction of the constrictor muscle leading to less light in the eyes

38
Q

Atropine is what kind of drug? and effects the eyes how?

A

M3 antagonists, thus leading to pupil dilation (inhibits the constrictor muscle)

39
Q

Carbachol is what kind of drug? and has what effect on the eyes

A

M3 agaonist, thus promoting pupil constriction via constrictor muscle

40
Q

Stimulation of M3 has what effect on the uterus?

A

Induces contractions

41
Q

Stimulation of B2 has what effect on the uterus?

A

Causes relaxation

42
Q

Terbutaline is what kind of drug?

A

B2 agonist, thus causing uterine relaxation. Can be used to prolong pregnancy if baby is coming out too early

43
Q

Midronine affects vasculature in what mechanism?

A

a1 agonist, thus increasing BP (vasoconstriction)

44
Q

Prazosin, terazosin, doxazosin affect vasculature in what mechanism?

A

a1 antagonist, thus decreasing BP (vasodilation)

Cardiology (18 decks)

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