Contraception ! Flashcards
Explain the 4 levels of the UKMEC and what they are used for
Guiding the decision to start someone on the combined oral contraceptive pill
- UKMEC 1 = No restriction in use
- UKMEC 2 = Benefits generally outweigh risks
- UKMEC 3 = Risks generally outweight benefits
- UKMEC = Unacceptable risk (CI)
What is a UKMEC 3 for the COCP?
- More than 35 years old and smoking less than 15 cigarettes/day
- BMI > 35 kg/m^2*
- Family history of thromboembolic disease in first degree relatives < 45 years
- Controlled hypertension
- Immobility e.g. wheel chair use
- Carrier of known gene mutations associated with breast cancer (e.g. BRCA1/BRCA2)
- Current gallbladder disease
UKMEC 4 for the combined contraceptive pill
- Uncontrolled hypertension (particularly ≥160 / ≥100)
- Migraine with aura
- History of VTE
- History of stroke or IHD
- Aged over 35 smoking more than 15 cigarettes per day
- Current breast cancer
- Major surgery with prolonged immobilisation
- Systemic lupus erythematosus and antiphospholipid syndrome
- Breast feeding < 6 wks post-partum
Mechanismof action of the combined oral contraceptive pill (COCP)
Inhibits ovulation
What advice is given if one COCP is missed (less than 72 hrs since last pill)
-Take missed pill as soon as possible (even if 2 on same day)
-No extra protection required provided other pills before where taken correctly
Advice if 2 missed pills when on the COCP
-Take most recent missed pill
-Additional contraception needed until pill has been taken for 7 days straight
-If this was missed on day 1-7 of the packet and they have had unprotected sex they will need emergency contraception
What are the 3 common regimes for taking the COCP?
- 21 days on and 7 days off
- 63 days on (three packs) and 7 days off (“tricycling“)
- Continuous use without a pill-free period
Give three risks of the COCP
- Small risk of VTE
- Small increased risk of breast and cervical cancer (returns to normal 10 yrs after stopping).
- Small increased risk of MI and stroke
If started within first 5 days of the cycle , when does the COCP offer protection ?
Straight away
No additional contraception needed
If the COCP is started after day 5 of the menstrual cycle, how long is barrier contraception required for ?
7 days
Advantages of the COCP
- Reduced risk of ovarian and endometrial cancer
- Reduced risk of colorectal cancer
- Often makes periods regular, lighter and less painful
Explain the cycle for the combined contraceptive patch
- Worn for 4 weeks
- First 3 weeks : patch worn every day and changed each week
- No patch worn in week 4 = withdrawal bleed
Explain precautions needed if there is a delay to changing the combined contraceptive patch in week 1 or 2
- <48 hr delay : change immediately, no further precautions
- Delay >48 hrs : chnage and use condoms for 7 days.
Explain precautions needed if there is a delay to patch removal at end of week three
- The patch should be removed as soon as possible and the new patch applied on the usual cycle start day for the next cycle, even if withdrawal bleeding is occurring.
-No additional contraception is needed.
What is required if patch application is delayed at the end of a patch-free week
- Additional barrier contraception should be used for 7 days following any delay at the start of a new patch cycle
How doe traditional POPs work ?
- Thickening the cervical mucus
How does desogestrel work (POP) ?
- Inhibiting ovulation
- Thickening the cervical mucus
If started on day 1-5 of the menstrual cycle, when does the POP provide protection ?
Immediately
Potential SE of POP
Irregular vaginal bleeding
If started after day 5 of the cycle, how long is barrier contraception required when on the POP
2 days
Explain the precautions regarding missed pills with the traditional POP
- If < 3 hours late: continue as normal
- If > 3 hours : take the missed pill as soon as possible, condoms, should be used until pill taking has been re-established for 48 hours
Explain the precautions regarding missed pills with desogestrel (Cerazette)
- <12 hrs : take pill & no extra precautions
- > 12 hrs : use condoms until pill taking has been re established for 48 hrs
Mechanism of action of nexplanon
- Primarily inhibits ovulation but ALSO thickens cervical mucus
- Involves the hormone etonogestrel (progestogen)
How long does nexplanon
last
3 yrs
Adverse effects of nexplanon
- Irregular/heavy bleeding : sometimes managed with co-prescription of COCP
UKMEC 4 for nexplanon
current breast cancer
If not inserted on day 1-5 of cycle, how long is additional contraception needed for with nexplanon
7 days
Contents and mechanism of action of injectable contraceptives
- Inhibits ovulation but ALSO thickens cervical mucus and causes endometrial thinning
- Contains medroxyprogesterone acetate 150mg
How often are injectable contraceptives given
Every 12 wks
How long can fertility be delayed once stopped injectable contraceptives
12 mnths
4 adverse effects of injectable contraceptives
- Irregular bleeding
- Weight gain
- Potentially increased risk of osteoporosis
- Not quickly reversible and fertility may return after a varying time
Mechanism of action of IUD
- Prevention of fertilisation by causing decreased sperm motility and survival (possibly an effect of copper ions)