Connective Tissues Flashcards

1
Q

Give examples of connective tissues

A

Bone, cartilage, tendons and ligaments, adipose tissue, mesentery, layers under skin and around organs

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2
Q

How is structure related to function?

A

Diverse structural arrangement depending on location and function of tissue

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3
Q

What features define connective tissues?

A

Ground substance, fibres and cells

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4
Q

What makes up the extracellular matrix?

A

Ground substance and fibres

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5
Q

What does the extracellular matrix do?

A

Provides structural and biochemical support for cells

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6
Q

What is the function of ground substance?

A

provides biochemical support and supports intercellular exchange of substances

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7
Q

What is ground substance?

A

Clear, semi-solid gel composed of glycoproteins and complex carbohydrates (hyaluronic acid and glucosamine)

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8
Q

What do fibres do?

A

Provide structural support and tensile strength

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9
Q

What are the two main types of fibres?

A

Collagen and elastin

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10
Q

Describe collagen fibres

A

Strongest and most abundant, provide tensile strength

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11
Q

Describe elastin fibres

A

Long and branched, provide stretch and recoil ability

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12
Q

Where does collagen come from?

A

It is secreted into the ECM by connective tissue cells

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13
Q

What is type 1 collagen?

A

found in fibrous tissues

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14
Q

What is type 2 collagen?

A

Hyaline cartilage

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15
Q

What is type 3 collagen?

A

delicate branched ‘reticular’ network found in highly cellular organs

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16
Q

Where does elastin come from?

A

It is secreted into the ECM by fibroblasts

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17
Q

What does elastin do?

A

Confers elasticity to tissues

18
Q

Where is elastin found?

A

Skin, lungs, blood vessels, bladder

19
Q

What do the cells of the connective tissues do?

A

synthesise, secrete and recycle ECM

20
Q

What do blasts do?

A

Synthesise ECM

21
Q

What do cytes do?

A

Maintain ECM

22
Q

What do clasts do?

A

Breakdown ECM

23
Q

What do fibroblasts do?

A

secrete fibres and components of ground substance

24
Q

What do chondrocytes do?

A

secrete and maintain ECM in cartilage

25
Q

What do osteoblasts and osteocytes do?

A

Secrete and maintain mineralised ECM in bone

26
Q

What do connective tissues contain?

A

Blood vessels and lymphatics. Immune cells which survey tissues for invading pathogens/cell damage

27
Q

What is connective tissue proper?

A

loose or dense depending on arrangement of fibres

28
Q

What is skeletal connective tissues?

A

Cartilage and bone

29
Q

What is fluid connective tissues?

A

blood and lymph

30
Q

What is loose connective tissues?

A

Mostly made up of ground substance. Areolar, adipose and reticular

31
Q

What is dense connective tissues?

A

Mostly made up of fibres. Regular, irregular and elastic

32
Q

What is areolar tissue and where is it found?

A

Universal packing material which supports and binds other tissues. It is found beneath skin, submucosa and surrounding capillaries

33
Q

What is adipose tissue and where are they found

A

Function as energy storage, shock absorption and insulation. Found beneath skin, breasts, in abdomen, finger and foot pads.

34
Q

Where are adipocytes found?

A

In isolation or in small clusters

35
Q

What is reticular tissue and where is it found?

A

Delicate, branched network providing internal structure to highly cellular organs (liver, lymph nodes, spleen)

36
Q

What is dense regular tissue and where is it found?

A

closely packed collagen fibres running in the same direction. provides tensile strength and found in tendons and ligaments

37
Q

What is dense irregular tissue and where is it found?

A

closely packed interwoven fibres running in different directions. found in dermis of skin, forms protective capsule around organs

38
Q

What is elastic dense tissue and where is it found?

A

allows tissues to recoil after stretching. found in arteries, skin, lungs and underlying transitional epithelium

39
Q

What is scurvy and what are the oral manifestations?

A

Lack of vitamin C leading to defective collagen formation. Leads to loose teeth, skin haemorrhages and even death

40
Q

What is systemic lupus erythematosis and what are the oral manifestations?

A

autoimmune disease. target skin, bones, tendons and kidneys. Oral symptoms include dryness and soreness. Oral manifestations include buccal and palatal lesions.

41
Q

What is sjogren’s disease and what are the oral manifestations?

A

autoimmune disease affecting saliva and tear glands. dry eyes and mouth, occur independently of accompany other disorders. Can cause increased dental caries ad candidiasis.