Connective Tissue Part 2

Question 1

Function of fibroblasts?

Answer 1

produce fibers and ground substance

Question 2

Endothelial cells interaction and function?

Answer 2

• pericyte = stem cell of endothelial cell
• basement membrane
• lines blood vessels (continuous vs fenestrated - open)

Question 3

Function of mast cells?

Answer 3

mediate allergic and inflammatory response
- composed of granules

Question 4

What does a mast cell contain?

Answer 4

react to antigens to release granules
- heparin (prevent blood clots)
- histamine (blood vessels leak)
- chemotactic factors (contract smooth muscle)

Question 5

Function of macrophages?

Answer 5

remove senescent cells, cellular debris, invading organisms, cancer cells
- from blood monocytes

Question 6

Function of plasma cells?

Answer 6

• secrete antibodies
• from activated beta-lymphocytes
• negative golgi with clock-face nucleus

Question 7

3 types of leukocytes and their functions?

Answer 7

neutrophils – migrate and kill foreign cells
eosinophils – fight parasites
lymphocytes – trigger immune response

Question 8

Loose CT location, ratio, function, components?

Answer 8

• under epithelium
• cells>fibers
• carry vessel and nerves
• Type I and III collagen + elastic fibers

Question 9

Dense RCT location, ratio, function?

Answer 9

• ligaments
• fibers>cells
• minimal regeneration
• collagen bundles one direction and fibroblasts

Question 10

Dense IR CT location, ratio, function, components?

Answer 10

• between organs
• fibers>cells
• resilient and protective
• collagen bundles diverse and fibrocytes (in rows)

Question 11

Reticular CT location, function and components?

Answer 11

• hematopoietic organs
• lymphocyte migration
• type III collagen

Question 12

Adipose tissue function?

Answer 12

stores fat
- similar to loose CT

Question 13

Brown vs White adipose tissue?

Answer 13

Brown
- lipid droplets broken b/c lots of mitochondria
- heat generation

White
- lipid vacuole with peripheral nucleus