Connective Tissue Flashcards
What are the two kinds of embryonic connective tissue?
1.mesenchyme; 2.mucous
What are the two major kinds of connective tissue?
Embryonic and adult connective tissue
What are the six main functions of connective tissue?
1.binds, supports, and strengthens; 2.protection; 3.insulation; 4.compartmentalization; 5.transport; 6.storage of energy reserves; 6.immune responses
What are the three characteristics of connective tissue?
A.cells in an extracellular matrix; B.Common origin; C.degrees of vascularity
What is the stem cell that all connective tissues arise from?
Mesenchymal stem cell or a mesenchymal cell
What are the two parts of the extracellular matrix?
1.protein fibers; 2.ground substance
What are the three types of protein fibers?
A.collagen; B.reticular; C.elastic
What are the three components of ground substance?
A.glycosaminoglycans (GAGs); B.proteoglycans; C.multiadhesive glycoproteins (lamin and fibronectin)
What is the major product, activity or function of a fibroblast, chondroblast, osteoblast, or odontoblast?
Production of fibers and ground substance, and a structural function.
What is the major product, activity or function of a plasma cell?
Production of antibodies and immunologic function
What is the major product, activity or function of a lymphocyte?
Production of immunocompetent cells and immunologic function
What is the major product, activity or function of a eosinophil?
Participation in an allergic and vasoactive reactions, modulation of mast cell activities and the inflammatory response, and immunologic function.
What is the major product, activity or function of a neutrophil?
Phagocytosis of foreign substances, bacteria and has a defense function.
What is the major product, activity or function of a macrophage?
Secretion of cytokines and other molecules, phagocytosis of foreign substances and bacteria, antigen processing and presentation to other cells and the major function is defense.
What is the major product, activity or function of a mast cell, basophil?
LIberation of pharmacologically active molecules (eg histamine) and its major function is defense
What is the major product, activity or function of an adipose cell?
Strorage of neutral fats and thermogenesis
Will active fibroblasts have a more euchromatin or heterochromatin?
There will be more euchromatin
How do collagen fibers stain?
Very eosinophilic
What is a myofibroblast?
This is an elongated cell similar to smooth muscle and fibroblast. There are actin filaments associated with this cell giving it some movement by pulling on the extracellular matrix.
What is the size range of mast cells?
20-30 micrometers, they are large. Several RBCs could line up across one of these cells.
What is the cytoplasm of mast cells mainly composed of?
Very basophilic secretory granules which are 0.3 - 2.0 micrometers in diameter and a nucleus.
What do mast cells contain that play roles in immunity, tissue repair, and allergic response?
Histidine and heparin
What cell does a plasma cell come from?
B lymphocytes
Plasma cells stain very basophilic because of what in the cytoplasm?
All the rough ER.
What cells have nuclei that look like cart wheels or clocks?
plasma cells, they have clumps of heterochromatin around the periphery of they nucleus.
What cell are macrophages derived from?
Macrophages come from monocytes
Macrophages have many what in the cytoplasm?
Lysosomes
Describe what a macrophage looks like?
very indistinct PM, almost foamy appearance, and a clearly visible cytoplasm