Connective tissue Flashcards
Connective tissue function and components
Extracellular matrix and cells
Binds, supports and strengthens tissues, transport system, stores energy
Extracellular matrix functions and components
Ground substance and protien fibres
ECM structure determines CT qualities
Ground substance components and function
Water, Sugars (Gylcosominoglycans), protiens
Gylcosaminoglycans
Repeating sugar units that bond to core protiens forming proteoglycans - trapping water to make ground substance jelly like
Hyaluronic acid
Non sulphated GAG binds to PGs to provide lubrication
Chondroitin sulphate
Sulphated GAG supprots ahdesive features of bone, skin and blood
Exophthalmos
Abnormal periorbital (EYE) ECM and thyroid disease leading to bulging eyes
Collagen fibre
Strong and flexible to resist forces - In bones
Reticular fibre
Collagen coated in glycoprotiens provide strength and support
Elastic fibres
Most flexible and returns to original state state - In skin
Fibroblast
Secrete ECM substances
adipocytes
stores fat
Mast cells
Make histamine that dilate vessels in immune response
Macrophage
Phagocytes in lungs and infection sites
Plasma cell
Form B cells and antibodies
Leucocytes
White blood cells - Eosinphill, neutrophils
Embryonic CT - Mesenchyme function and components
Gives rise to all CT - Ground susbtance and reticular fibres
Embryonic CT - Mucous function and components
Support umbilical cord - Fibroblasts
Mature CT - Loose areolar
Contain reticular, elastin, collagen fibres for strength, stability and support
Mature CT - Loose Adipose
White adipose stores energy and Brown adipose produce heat, energy, thermoregulation
Mature CT - Loose reticular and location
Mainly reticular fibres for strcuture support - Marrow, liver, kidney
Mature CT - Dense irregular
Unbundled collagen to resist tearing forces
Mature CT - Dense regular
Bundled collagen to resist pulling forces in skeletal structuree
Mature CT - Dense elastic
Mainly elastic and collagen to resist permanent stretch
