Connective Tissue Flashcards
What is the function of connective tissue?
- comprises much of the body and is the most abundant type of tissue by weight
- Binds structures
- Provides support and protection
- Serves as frameworks
- fills spaces
- Stores fat
- Produces blood cells
- Protects against infection and repairs tissue damage
What are the general characteristics of connective tissue?
- Cells are farther apart and have an abundant extracellular matrix between them
What is an extracellular matrix?
- Is composed of protein fibers and a ground substance consisting of nonferrous protein and other molecules and fluid
- Binds supports, and provides a medium thru with substances may be transferred between blood and cells of tissue
What’s the consistency of the extracellular matrix?
Varies from fluid/semisolid to solid
What are the major cell types in CT?
- Fibroblasts
- Macrophages
- Mast cells
What are the general characteristics of fibroblasts?
- The most common type of fixed cells in CT.
- Large/star-shaped cells
- Produce fibers by secreting proteins into the extracellular matrix
- Respond rapidly to injury by increasing # of fiber production
- Help repair tissue
What are the general characteristics of macrophages?
- Histiocytes
- Usually attached to fibers but can detach and actively move about
- Specialized to carry on phagocytosis (the exocytosis of large particles/viruses/microorganisms_
- Clear foreign particles from tissues, provides defense against infection
- Plays role in immunity
What are the general characteristics of mast cells?
- Widely distributed in CT
- Usually are near blood vessels
- Derived from white blood cells
- Release heparin (compound that prevents blood clotting)
Which cell releases histamine?
- Mast cells release histamine.
- Stimulates inflammation by dilating the small arterioles that feed the capillaries
- Is inhospitable to infections, bacteria and viruses
- also dilutes toxins
WHAT ARE THE SIX COMPONENTS OF CONNECTIVE TISSUE?!
CELLULAR: - Fibroblasts, macrophages, mast cells EXTRACELLULAR: - Collagen, elastic, reticular fibers - Ground substance
What is the function of Collagen fibers?
- Thick, threadlike structures
- The body’s main structural protein
- Great tensile strength; slightly elastic
- Found in ligaments and tendons
What is the function of Elastic fibers?
- Bundles of microfibrils embedded in elastin
- Provides elastic quality to parts that stretch
- Not as strong as collagen fibers
- Found in vocal cords, respiratory air passages
What is the function of reticular fibers?
- Thin fibers of collagen
- Forms delicate supportive networks within tissues
- Found in the spleen/liver
What is the function of ground substance?
- nonfibrous protein and other molecules, and varying amounts of fluid
- Fills spaces around cells and fibers
WHAT ARE THE TWO MAJOR CATEGORIES OF CT?
- Ct proper
- Specialized CT
What is CT proper?
- Includes loose CT tissue
(Areolar, adipose, reticular) - and DENSE CT
(Dense regular, irregular, and elastic)
What are the general characteristics of dense CT? and loose CT?
Dense CT: - Contains abundant collagen fibers - Appears white Loose CT: - Has fewer collagen fibers
General characteristics of Areolar CT
- Forms delicate, thin membranes thru-out the body
- Mainly fibroblasts that are located some distance apart and are separated by a gel-like ground substance that contains collagen and elastic fibers
- binds skin to underlying organs
- Beneath most epithelium layers/nourishes blood vessels near epithelial cells
General characteristics of adipose
- adipocytes store fat
- push their nuclei to one side
- crowd out other cell types
- protects/cushions/insulates
- Beneath skin
- Behind eyeballs
- Around kidney/heart
- spaces between muscles