concepts

Question 1

half life

Answer 1

the time it takes for the serum concentration of drug in the body to decrease 50% the peak level

Question 2

first pass effect

Answer 2

drug gets metabolized at a specific location in the body that results in a reduced concentration of the active drug upon reaching its site of action or the systemic circulation
oral drugs

Question 3

tolerance

Answer 3

drug becomes accustomed to a particular drug over time
requires larger dose to produce the same effect

Question 4

protein bound

Answer 4

when bound inactivated
when inbound activated
highly protein bound high affinity longer time to reach therapeutic effect

Question 5

toxicity

Answer 5

poisoning or overdose of the drug
results from excessive amounts of drugs and can cause damage to the tissues
check if patient is breathing or not breathing

Question 6

sources of drug information

Answer 6

Drug labels and package inserts
Most accurate source due to FDA regulations
Drug reference books
Includes point of care reference and Electronic Medical Record (EMR)
Journals
Internet sites
Carefully scrutinize-use government sites and nursing/Health Care sites only