Colorectal Carcinoma Flashcards
1
Q
Define colorectal carcinoma
A
The majority of colorectal cancers are adenocarcinomas derived from epithelial cells
2
Q
Explain the aetiology / risk factors of colorectal carcinoma
A
Age APC mutation HNPCC MYH- associated polyposis Hamartomatous polyposis syndrome IBD Obesity Acromegaly Limited physical activity Lack of dietary fibre
3
Q
Summarise the epidemiology of colorectal carcinoma
A
Colorectal cancer is the third most common cancer in the Western world.
The lifetime risk of developing colorectal cancer is 5.42%.
4
Q
What are the signs and symptoms of colorectal carcinoma?
A
Rectal Bleeding Change in Bowel habit Rectal mass Abdominal mass Anaemia Weight loss/ anorexia Distension Palpable lymph nodes
5
Q
What are appropriate investigations for colorectal carcinoma? and interpret the results
A
> Local excision/ radical resection
Preoperative/ perioperative/ postoperative Chemoradiotherapy/ radiotherapy
Monoclonal Ab
stenting (Adjunct)
