Cole Histology and Development Flashcards
Filiform papillae location
most medial aspect of tongue
Filiform papillae structure
most abundant
Filiform papillae function
hold onto food and anything being masticated
Fungiform papillae location
middle aspect of tongue
lateral to filiform
Fungiform papillae structure
nonkeratinized stratified squamous
Circumvallate papillae location
posterior part of tongue in front of sulcus terminalis
Circumvallate papillae structure
surrounded by trench
Circumvallate papillae function
have hundreds of taste buds and where you can suspend food
Foliate papillae location
side of tongue
Foliate papillae structure
have serous glands on top, taste buds in lateral wall
Foliate papillae function
not well developed in humans but is in other animals
3 components of taste buds
taste receptor, supporting cells, and precursor cells (basal cells)
Taste receptor - basal portion
contacts afferent nerve terminal derived from sensory ganglia of the facial, glossopharyngeal and vagus nerves
How long do taste buds last?
2 weeks and then remade
Supporting cells
immature taste buds that turn into mature taste buds
Precursor cell- basal cell
give rise to supporting cell
Ebner’s gland location
in connective tissue and in all things that have taste buds
What 2 papillae is Ebner’s glands associated with
foliate and circumvallate
Ebner’s gland secretions
secrete lingual lipase and VEGP
VEGP
Von Ebner’s gland protein
VEGP function
binds flavorful chemicals and helps pick up and transport food
Tastents
soluble chemical taken into the taste bud
Taste receptor subunits
G protein, a b, y subunits
Taste receptor function
tastents interact with subunit
Location of Taste receptors
apical microvilli of taste receptors
6 confirmed taste
sweet, salty, sour, bitter, umami, fat
Location of sweet
tip of tongue
Sweet flavor
sugars
Location of salty
posterior and lateral to tip of the tongue
Salty flavor
sodium
Location of sour
anterior 2/3 of dorsum and along the lateral margin
Sour flavor
acidic, H+
Location of bitter
posterior, medial tongue
Bitter flavor
caffeine, morphine, and nicotine
Location of Umami
Unknown
Umami flavor
L glutamate and other amino acids
What does a fat taste detect
texture of fat
Nasal cavity structure - respiratory function
lined with pseudostratified columnar epithelium and goblet cells
Lamina propria in nasal cavity
contains both serous and mucous glands to moisten air and trap particles
Functions of Nasal mucosa
air hydrations, air filtration, and temperature regulation
Air hydration
secrete serous and mucous exocrine glands and goblet cells to moisten the surface of nasal cavity
- add water vapor to inspired air
Air filtration
conchae interrupt air flow and create turbulence
matter adheres to conchae and cilia moves it to nasopharynx
Temperature regulation
can warm or cool inspired air
Structure of olfactory epithelium
pseudostratified columnar with 2 types of cells - olfactory cells, supporting cells, and basal cells
Olfactory cells
bipolar sensory neurons where dendrite extends and dilates to from olfactory vesicle
Supporting cells of Olfactory epithelium
sustentacular cells, columnar cells with oval nuclei
Function of supporting cells of olfactory epithelium
provide physical support, nourishment and electrical insulation of the olfactory cell
Olfactory bulb
axon terminals connect with synaptic terminals of mitral cells
Mitral cells
connect olfactory bulb to make glomeruli
Glomeruli
connection between axon terminals of olfactory bulb and mitral cells
Kallman Syndrome
dont have sense of smell because don’t make GnRH –> dont make LH –> dont have gonadal dvpt
Anosmia for Kallman Syndrome
lack of neurons in the brain (mitral cells) that receive input from olfactory neurons
Defective gene in Kallman Syndrone
KAL1
look at drawing of olfaction process
ok
