coeliac Flashcards
what alcoholic beverage contains gluten?
beer
does bread have gluten?
yes
does pasta have gluten?
yes
does rice have gluten?
no
does potatoes have gluten?
no
does oats have gluten?
yes
what molecule in gluten is most pathogenic?
gliadin
gliadin is deamidated by what enzyme?
which antibody is made against this enzyme?
tissue transglutaminase
IgA
which genes are almost always implicated in coelaic?
-2
HLA-DQ2 or HLA-DQ8
what is the hallmark of coeliac?
malabsorption
which type of WBC is mainly implicated in coeliac?
lymphocytes
what happens to crypts?
hyperplasia
HLA-DQ2 presents peptides to what immune cell?
T-helper cell
which syndromes are associated with coeliac?
-2
Down’s syndrome
Turner’s syndrome
which autoimmune diseases are associated with coeliac?
-2
T1DM
autoimmune thyroid disease
histology of duodenum in coeliac?
-2
villous atrophy
crypt hyperplasia