Alcohol: units Flashcards

1
Q

recommended units of alcohol per week?

A

14

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2
Q

is it recommended to binge drink your unit allowance in one day or spread it out through the week?

A

spread through the week

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3
Q

should pregnant women drink?

A

no

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4
Q

is it recommended that a woman looking to get pregnant can drink?

A

no

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5
Q

how many ml of pure ethanol in one unit of alcohol?

A

10

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6
Q

equation for calculating units?

A

(ml x ABV)/1000

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7
Q

what does ABV stand for?

what is the unit?

A

alcohol by volume

%

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8
Q

how many ml in one pint?

A

568

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9
Q

why do alcoholics get alcoholic ketoacidosis?

A

eat irregularly + vomit = starvation = malnourished = body breaks down fat to use ketones

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10
Q

what is ABG result in alcoholic ketoacidosis?

A

o Metabolic acidosis with elevated anion gap

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11
Q

acute treatment of alcoholic ketoacidosis?

-2

A

IV saline

+ thiamine

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12
Q

why is thiamine given?

A

stop Wernicke’s encephalopathy

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13
Q

what is the Wernicke’s encephalopathy triad?

A

ataxia
confusion
eye signs

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14
Q

AST:ALT ratio > 3 suggest what conition?

A

acute alcoholic hepatitis

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15
Q

In an acute setting what do you give for acute alcoholic hepatitis?

  • 1
  • drug name
A

prednisolone

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16
Q

Alcoholic liver disease is a spectrum,

what 3 diseases does it cover?

A

alcoholic fatty liver disease

alcoholic hepatitis

cirrhosis

17
Q

through what mechanisms does alcohol damage the liver?

A

Ethanol –> breaks down to acetaldehyde –>disrupts cytoskeleton and metabolite function

Ethanol oxidized –> ROS made

ROS stimulated cytokine release –> IL-1, IL-6,, IL-8, TNF –> injure cells

18
Q

what happens to ketone and glucose levels in alcoholic ketoacidosis?

A

o Elevated serum ketone levels

o Normal or low glucose concentration

19
Q

Ethanol breaks down into what?

A

acetaldehyde