Coagulation/transfusion Flashcards

1
Q

What are the stages of hemostasis

A

1 - plt plug, 2 fibrin clot, 3 fibrinolysis

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2
Q

What is an antifibrinolytic drug

A

Aminocaproic acid, tranexamic acid

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3
Q

What are indications for RBC transfusion

A

Anemia, decreased oxygen carrying capacity

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4
Q

What are indications for FFP transfusion

A

Coagulopathy, hypoproteinemia, oncotic support

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5
Q

What is in cryoprecipitate

A

VIII, vWF

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6
Q

What is a blood type

A

Antigens on RBC - species specific

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7
Q

What does DEA stand for

A

Dog erythrocyte antigen

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8
Q

What is the most important canine blood type

A

DEA 1.1

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9
Q

What % of the population is DEA 1.1 +

A

42%

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10
Q

What are feline blood types

A

A, B, AB

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11
Q

What breed is always A

A

Siamese

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12
Q

What are common B breeds

A

Devon rex, british shorthair, turkish angora, cornish rex, birman, himalayan

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13
Q

Cats with type ___ have very strong naturally occurring alloantibodies (likely have a severe transfusion reaction)

A

B

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14
Q

What is the lifespan of a dog RBC

A

100-120 days

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15
Q

What is the lifespan of a cat RBC

A

65-76 days

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16
Q

What is crossmatching

A

Major - recipient antibodies and donor rbc
Minor - donor antibodies and recipient RBC

17
Q

What are indications for crossmatch

A

Previous transfusion

18
Q

What is the most common transfusion reaction

A

Febrile non-hemolytic transfusion reaction

19
Q

What causes FNHTR

A

Cytokines

20
Q

Define FNHTR

A

Increase in temp by 1 C

21
Q

What are NON-immunologic transfusion reactions

A

Bacterial contamination
TACO
Citrate toxicity

22
Q

What is the mechanism of acute hemolytic transfusion reaction

A

Type II hypersensitivity reaction

23
Q

Define massive transfusion

A

Greater than blood volume in 24 hours
Greater than 50% blood volume in 3 hours

24
Q

What are the recommended ratios for massive transfusion

A

1:1:1

25
Q

What is FFP

A

Frozen within 8 hours of separation, less than a year

26
Q

What if FP

A

Frozen more than 8 hours after separation; more than 1 year; thawed and refrozen

27
Q

List transfusion reactions

A

FNHTR
Acute hemolytic transfusion reaction
TACO
TRALI
Anaphylaxis
Allergic reaction

28
Q

What are signs consistent with bacterial contamination of a unit of blood

A

Color change
Gas bubbles

29
Q
A